Ashrafi, Kaveh
Bernstein, Harold S.
Black, Brian L
Blanc, Paul D
Botvinick, Elias H
Boushey, Homer A
Broaddus, V Courtney
Brodsky, Frances M
Brown, James K
Bruneau, Benoit G
Caughey, George H
Chapman, Harold A
Charo, Israel F
Chatterjee, Kanu
Chuang, Pao-Tien
Clyman, Ronald I
Conklin, Bruce R
Conte, Michael S
Coughlin, Shaun R
Derynck, Rik M
Dobbs, Leland G
Eisner, Mark D
Engel, Joanne N
Erle, David J
Fahy, John Vincent
Farese, Robert V
Fielding, Christopher J
Fineman, Jeffrey R
Gardner, David G
Gartner, Zev Jordan
Glantz, Stanton A
Gold, Warren M
Gropper, Michael
Grossman, William
Hawgood, Samuel
Hill, Arthur C
Hoffman, Julien I
Ingraham, Holly A
Jan, Lily Y
Julius, David J
Kan, Yuet W
Kane, John P
Karliner, Joel S
Kornberg, Thomas B
Kurtz, Theodore W
Kwok, Pui-Yan
Lazarus, Stephen C
Lee, Randall J
Lim, Wendell A
Mahley, Robert W
Malloy, Mary J.
Mann, Michael J
Martin, Gail R
Matthay, Michael A
Mcdonald, Donald M
Mikawa, Takashi
Minor, Daniel L
Mostov, Keith E
Nadel, Jay A
Olgin, Jeffrey E
Pearce, David
Pittet, Jean-Francois
Redberg, Rita F
Reiter, Jeremy F.
Rosen, Steven D
Rowitch, David H
Scheinman, Melvin M
Schiller, Nelson B
Shaw, Robin M.
Sheppard, Dean
Shokat, Kevan M
Simpson, Paul C
Springer, Matthew L
Srivastava, Deepak
Stainier, Didier Y. R.
Teitel, David F
Von Zastrow, Mark E
Wang, Rong
Weiner, Orion D
Weiss, Arthur
Weiss, Ethan J
Werb, Zena
Woodruff, Prescott G
Xu, Allison Wanting
Young, William L

CVRI Scientists

Michael J Mann, M.D.

Research Interests:
1. Molecular/cellular biology and molecular genetics of atherosclerosis and heart failure. 2. Development of hybrid surgical and molecular/cellular therapies for heart disease. 3. Stem and progenitor cell transplantation for cardiovascular regeneration. 4. Cardiovascular tissue engineering. 5. Reduction to clinical practice of current methods in genetic, molecular and cellular disease intervention. 6. Novel targeted molecular therapies for lung cancer. 7. Molecular profiling of cancers for personalized medicine. 8. Development of novel methods of in vivo/ex vivo gene therapy and gene transfer. 9. Novel approaches to therapeutic neovascularization for coronary and peripheral ischemic disease. 10. Cardiovascular cell cycle biology. 11. Myocardial gene therapy.

Summary:
Dr. Mann's research focuses on the molecular and cellular biology of heart disease with an emphasis on practical ways to develop new treatments for heart failure. These involve potential gene and molecular therapies, combinations of molecular and cell-based treatments with surgical reconstruction, and evaluation of novel materials for the development of bioartificial replacements of lost or damaged heart tissue.

CVRIHead