Ashrafi, Kaveh
Bernstein, Harold S.
Black, Brian L
Blanc, Paul D
Botvinick, Elias H
Boushey, Homer A
Broaddus, V Courtney
Brodsky, Frances M
Brown, James K
Bruneau, Benoit G
Caughey, George H
Chapman, Harold A
Charo, Israel F
Chatterjee, Kanu
Chuang, Pao-Tien
Clyman, Ronald I
Conklin, Bruce R
Conte, Michael S
Coughlin, Shaun R
Derynck, Rik M
Dobbs, Leland G
Eisner, Mark D
Engel, Joanne N
Erle, David J
Fahy, John Vincent
Farese, Robert V
Fielding, Christopher J
Fineman, Jeffrey R
Gardner, David G
Gartner, Zev Jordan
Glantz, Stanton A
Gold, Warren M
Gropper, Michael
Grossman, William
Hawgood, Samuel
Hill, Arthur C
Hoffman, Julien I
Ingraham, Holly A
Jan, Lily Y
Julius, David J
Kan, Yuet W
Kane, John P
Karliner, Joel S
Kornberg, Thomas B
Kurtz, Theodore W
Kwok, Pui-Yan
Lazarus, Stephen C
Lee, Randall J
Lim, Wendell A
Mahley, Robert W
Malloy, Mary J.
Mann, Michael J
Martin, Gail R
Matthay, Michael A
Mcdonald, Donald M
Mikawa, Takashi
Minor, Daniel L
Mostov, Keith E
Nadel, Jay A
Olgin, Jeffrey E
Pearce, David
Pittet, Jean-Francois
Redberg, Rita F
Reiter, Jeremy F.
Rosen, Steven D
Rowitch, David H
Scheinman, Melvin M
Schiller, Nelson B
Shaw, Robin M.
Sheppard, Dean
Shokat, Kevan M
Simpson, Paul C
Springer, Matthew L
Srivastava, Deepak
Stainier, Didier Y. R.
Teitel, David F
Von Zastrow, Mark E
Wang, Rong
Weiner, Orion D
Weiss, Arthur
Weiss, Ethan J
Werb, Zena
Woodruff, Prescott G
Xu, Allison Wanting
Young, William L

CVRI Scientists

Dean Sheppard, M.D.
Professor In Residence

Research Interests:
In vivo function of integrins and molecular basis of lung diseases

Summary:
Dean Sheppard's laboratory studies how cells respond to and modify their surroundings using receptors called integrins. They have found important roles for integrins in lung and kidney fibrosis, septic shock, acute lung injury, asthma and stroke and are testing drugs targeting integrins in animal models and in people affected by these diseases.

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