Primary manuscripts (in reverse chronological order):

  1. Deo RC* Zhang J, Hallock LA, Gajjala, S, Nelson L, Fan E, Aras MA, Jordan C, Fleischman KE, Melisko M, Qasim A, Shah S, Bajcsy R. An End-to-End Computer Vision Pipeline for Automated Assessment of Cardiac Function by Echocardiography arXiv:1706.07342 (link)
  2. Friesen M, Camahort R, Lee YK, Xia F, Gerszten RE, Rhee EP, Deo RC, Cowan CA. Activation of IRF1 in Human Adipocytes Leads to Phenotypes Associated with Metabolic Disease. Stem Cell Reports 2017 May 9;8(5):1164-1173. doi: 10.1016/j.stemcr.2017.03.014. Epub 2017 Apr 13.
  3. Warren CR, O'Sullivan JF, Friesen M, Becker CE, Zhang X, Liu P, Wakabayashi Y, Morningstar JE, Shi X, Choi J, Xia F, Peters DT, Florido MH, Tsankov AM, Duberow E, Comisar L, Shay J, Jiang X, Meissner A, Musunuru K, Kathiresan S, Daheron L, Zhu J, Gerszten RE, Deo RC, Vasan RS, O'Donnell CJ, Cowan CA. Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease. Cell Stem Cell 2017 Apr 6;20(4):547-557.e7. doi: 10.1016/j.stem.2017.01.010.
  4. Deo RC* Alternative splicing, an internal promoter, nonsense-mediated decay, or all three: explaining the distribution of truncation variants in Titin. Circulation Cardiovascular Genetics 2016 Oct;9(5):419-425. Epub 2016 Sep 13.
  5. Odegaard JI, Lee MW, Sogawa Y, Bertholet AM, Locksley RM, Weinberg DE, Kirichok Y, Deo RC, Chawla, A. Perinatal Licensing of Thermogenesis by IL-33 and ST2. Cell 2016 Jul 20. pii: S0092-8674(16)30811-X. doi: 10.1016/j.cell.2016.06.040. (link)
  6. Zou J, Tran D, Baalbaki M, Tang LF, Poon A, Pelonero A, Titus EW, Yuan C, Shi C, Patchava S, Halper E, Garg J, Movsesyan I, Yin C, Wu R, Wilsbacher LD, Liu J, Hager RL, Coughlin S, Jinek M, Pullinger CR, Kane JP, Hart DO, Kwok PY, Deo RC* An Internal Promoter Underlies the Difference in Disease Severity between N- and C-terminal Truncation Mutations of Titin in Zebrafish. eLife 2015 Oct 16;4. doi: 10.7554/eLife.09406. (link)
  7. Vedantham V*, Galang G, Evangelista M, Deo RC*, and Srivastava D. RNA Sequencing of Mouse Sinoatrial Node Reveals an Upstream Regulatory Role for Islet-1 in Cardiac Pacemaker Cells. Circ Research 2015 Feb 27;116(5):797-803. doi: 10.1161/CIRCRESAHA.116.305913. Epub 2015 Jan 26. (link)
  8. Deo RC*, Musso G, Tasan M,, Tang P, Poon A, Yuan C, Felix JFF, Vasan RS, Beroukhim R, De Marco T, Kwok PY, MacRae CA, Roth FP*. Prioritizing Causal Disease Genes Using Unbiased Genomic Features. Genome Biology 2014, 15:3274 (link)
  9. Shah S*, Katz DH, Selvaraj S, Burke M, Yancy CW, Gheorghiade M, Bonow RO, Huang CC, Deo RC*. Phenomapping for Novel Classification of Heart Failure with Preserved Ejection Fraction. Circulation 2015 Jan 20;131(3)269-279 (link)
  10. Roberts JD, Longoria J, Poon A, Gollob MH, Dewland TA, Kwok PY, Olgin JE, Deo RC*, Marcus GM*. Targeted Deep Sequencing Reveals No Definitive Evidence for Somatic Mosaicism in Atrial Fibrillation. Circ Cardiovasc Genet 2014 Nov 18. pii: CIRCGENETICS.114.000650.
  11. Heredia JE, Mukundan L, Chen FM, Mueller AA, Deo RC, Locksley RM, Rando TA, Chawla A. Type 2 innate signals stimulate fibro/adipogenic progenitors to facilitate muscle regeneration. Cell. 2013 Apr 11;153(2):376-88.
  12. Rozenblatt-Rosen O*, Deo RC*, Padi M*, Adelmant G*, Calderwood MA, Rolland T, Grace M, Dricot A, Askenazi M, Tavares M, Pevzner S, Abderazzaq F, Byrdsong D, Carvunis Anne-Ruxandra, Chen AA, Cheng J, Correll M, Duarte M, Fan C, Ficarro SB, Franchi R, Garg B, Gulbahce N, Hao T, Holthaus AM, James R, Korkhin A,Litovchick L, Mar JC, Pak TR, Rabello S, Rubio R, Shen Y, Singh S, Spangle JM, Tasan M, Wanamaker S, Webber JT, Roecklein-Canfield J, Johannsen E, Barabasi AL, Beroukhim R, Kieff E, Cusick ME, Hill DE, Munger K, Marto JA, Quackenbush J, Roth FP, DeCaprio JA, Vidal M. Interpreting cancer genomes using systematic host perturbations by tumour virus proteins. Nature. 2012 Jul 26;487(7408):491-5.
  13. Ahfeldt T, Schinzel RT, Lee YK, Hendrickson D, Kaplan A, Lum DH, Camahort R, Xia F, Shay J, Rhee EP, Clish CB, Deo RC, Shen T, Lau FH, Cowley A, Mowrer G, Al-Siddiqi H, Nahrendorf M, Musunuru K, Gerszten RE, Rinn JL, Cowan CA. Programming human pluripotent stem cells into white and brown adipocytes. Nat Cell Biol. 2012 Jan 15;14(2):209-19. doi: 10.1038/ncb2411.
  14. Diep C, Ma D, Deo RC, Holm TM, Naylor RW, Arora N, Wingert RA, Bollig F, Djordjevic G, Lichman B, Zhu H, Ikenaga T, Ono F, Englert C, Cowan C, Hukriede NA, Handin RI, Davidson AJ. Identification of adult nephron progenitors capable of kidney regeneration in zebrafish. Nature. 2011 Feb 3;470(7332):95-100. Epub 2011 Jan 26. PMCID 274932.
  15. Lau FH, Deo RC, Mowrer G, Caplin J, Ahfeldt T, Kaplan A, Ptaszek L, Walker JD, Rosengard BR, Cowan CA. Pattern specification and immune response transcriptional signatures of pericardial and subcutaneous adipose tissue. PLoS One. 2011;6(10):e26092. Epub 2011 Oct 11.
  16. Becker JR, Deo RC, Werdich AA, Panakova D, Coy S, Macrae CA. Human cardiomyopathy mutations induce myocyte hyperplasia and activate hypertrophic pathways during cardiogenesis in zebrafish. Dis Model Mech. 2011 Jan 18. PMCID 274933
  17. Deo RC*, Wilson JG*, Xing C*, Lawson K, Kao L, Reich D, Tandon A, Akylbekova E, Patterson N, Mosley TH, Boerwinkle E, Taylor HA. Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans. PLoS One 6(1): e14581. doi:10.1371/journal.pone.0014581
  18. Keebler M*, Deo RC*, Surti A, Konieczokwsi, Guiducci C, Burtt N, Buxbaum SG, Sarpong DF, Steffes MW, Wilson JG, Taylor HA, Kathiresan S. Fine-mapping in African Americans of Eight Recently Discovered Genetic Loci for Plasma Lipids: The Jackson Heart Study. Circulation Cardiovascular Genetics. 2010 Aug;3(4)358-64. Epub 2010 Jun 22.
  19. Lewis GD, Farrell L, Wood MJ, Martinovic M, Arany Z, Rowe GC, Souza A, Cheng S, McCabe EL, Yang E, Shi X, Deo R, Roth FP, Asnani A, Rhee EP, Systrom DM, Semigran MJ, Vasan RS, Carr SA, Wang TJ, Sabatine MS, Clish CB, Gerszten RE. Metabolic signatures of exercise in human plasma. Science Transl Med. 2010 May 26;2(33):33ra37. PMCID: PMC2829050
  20. Deo RC, Hunter L, Lewis GD, Pare G, Vasan R, Chasman D, Wang TJ, Gerszten RE, Roth FP. Interpreting Metabolomic Profiles using Unbiased Pathway Models. PLoS Comp. Biol. 2010 Feb 26;6(2):e1000692. PMCID: PMC2823807
  21. Fejerman L, Haiman C, Reich D, Tandon A, Deo RC, John E, Ingles S, Ambrosone C, Bovbjerg D, Jandorf L, Davis W, Ciupak G, Whitemore A, Press M, Ursin G, Berstein L, Huntsman S, Henderson B, Ziv E, Freedman M. An Admixture Scan in 1,484 African American Women with Breast Cancer. Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):3110-7. Epub 2009 Oct 20.
  22. Deo RC, Reich D, Tandon A, Akylbekova E, Patterson N, Waliszewska A, et al. Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study. PLoS Genet. 2009;5(1):e1000342. PMCID: 2613537.
  23. Deo RC, Patterson N, Tandon A, McDonald GJ, Haiman CA, Ardlie K, et al. A high-density admixture scan in 1,670 African Americans with hypertension. PLoS Genet. 2007;3(11):e196. PMCID: 2077893.
  24. 2004 and Prior:

  25. Deo RC*, Schmidt EF*, Elhabazi A, Togashi H, Burley SK, Strittmatter SM. Structural bases for CRMP function in plexin-dependent semaphorin3A signaling. EMBO J. 2004;23(1):9-22. PMCID: 1271659.
  26. Collavoli A, Hatcher CJ, He J, Okin D, Deo R, Basson CT. TBX5 nuclear localization is mediated by dual cooperative intramolecular signals. J Mol Cell Cardiol. 2003;35(10):1191-5.
  27. Deo RC*, Groft CM*, Rajashankar KR, Burley SK. Recognition of the rotavirus mRNA 3' consensus by an asymmetric NSP3 homodimer. Cell. 2002;108(1):71-81.
  28. Khaleghpour K, Svitkin YV, Craig AW, DeMaria CT, Deo RC, Burley SK, et al. Translational repression by a novel partner of human poly(A) binding protein, Paip2. Mol Cell. 2001;7(1):205-16.
  29. Deo RC, Sonenberg N, Burley SK. X-ray structure of the human hyperplastic discs protein: an ortholog of the C-terminal domain of poly(A)-binding protein. Proc Natl Acad Sci U S A. 2001;98(8):4414-9. PMCID: 31849.
  30. Deo RC, Bonanno JB, Sonenberg N, Burley SK. Recognition of polyadenylate RNA by the poly(A)-binding protein. Cell. 1999;98(6):835-45.

*contributed equally

Reviews and Editorials (in reverse chronological order):

  1. Deo RC. Editorial commentary: Induced pluripotent stem cell (IPSC) cardiomyocytes: My kingdom for a useful disease model!. Trends Cardiovasc Med 2016 May 24. pii: S1050-1738(16)30053-6. doi: 10.1016/j.tcm.2016.05.009.
  2. Deo RC. Machine Learning in Medicine. Circulation 2015 Nov 17;132(20):1920-30. doi: 10.1161/CIRCULATIONAHA.115.001593. Review.
  3. Shah SJ, Katz DH and Deo RC. Phenotypic Spectrum of Heart Failure with Preserved Ejection Fraction. Heart Failure Clin 2014 Jul; 10(3):407-18
  4. Deo RC and MacRae CA. Clinical screening and genetic testing. Clin Lab Med. 2010 Dec;30(4):775-84.
  5. Deo RC and MacRae CA. The zebrafish: scalable in vivo modeling for systems biology. Wiley Interdiscip Rev Syst Biol Med 2010 Sep 29.
  6. Deo RC and Roth FP. Pathways of the Heart. Circulation Cardiovascular Genetics 2009; 2(4):303-305. PMCID: PMC2823807
  7. Deo RC and MacRae, CA. What the practicing cardiologist needs to know about genetics and heart disease. Heart and Metabolism. Number 41, 2008.
  8. Becker MM, Arold ST, Burley SK, Deo RC, Groft CM, Vitour D, Poncet D. Function and Structure of Rotavirus NSP3. In: John T. Patton , editor. Segmented Double-Stranded RNA Viruses: Structure and Molecular Biology. Ed., Horizon Scientific Press; 2008. p. 291-306.
  9. Deo RC and MacRae, CA. The Genetics of Cardiomyopathies: What Clinicians Should Know. Heart Failure Reports 2007, 4:229.