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| 2009 | ||
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Published in
the Handbook of Cell Signaling, 2nd Edition, Chapter author: Daniel L.
Minor, An Overview of Ion Channel Structure., Pages 201-208, Copyright
Elsevier (2009) Chatelain, F.C., Gazzarrini, S., Fujiwara, Y., Arrigoni, C., Domigan,
C., Ferrara, G., Pantoja, C., Thiel, G., Moroni, A., Minor, Jr., D.L.,
Selection of Inhibitor-Resistant Viral Potassium Channels Identifies a
Selectivity Filter Site that Affects Barium and Amantadine Block PLoS ONE Vol
4 Issue 10 e7496 (2009) Minor, Jr., D.L., Searching for interesting channels: pairing selection
and molecular Xu, Q., Minor, Jr., D.L., Crystal structure of a trimeric form
of the KV7.1 (KCNQ1) A-domain tail coiled-coil reveals structural plasticity
and context dependent changes in a putative coiled-coil trimerization
motif. Protein Science 18:2100—2114 (2009) Findeisen, F., Minor, Jr., D.L., Disruption of the
IS6-AID Linker Affects Voltage-gated Calcium Channel Inactivation and Facilitation. The
Journal of General Physiology 133 No. 3, 327-343 (2009) Hammon, J., Palanivelu, D.V., Chen, J., Patel, C., Minor, Jr., D.L. A
green fluorescent protein screen for identification of well-expressed
membrane proteins from a cohort of extremophilic organisms. Protein
Science 18, 121-133 (2009) |
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| 2008 | ||
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Balss, J., Papatheodorou, P., Mehmel, M., Baumeister, D.,
Hertel, B., Delaroque, N., Chatelain, F.C., Minor, Jr., D.L.,
Van Etten, J.L.,
Rassow, J., Moroni, A., Thiel, G., Transmembrane domain length of viral
K channels is a signal for mitochondria targeting. PNAS 34,
12313-12318 (2008) Fujiwara, Y., Minor, Jr., D.L. X-ray
Crystal Structure of a TRPM Assembly Domain Reveals an Antiparallel Four-stranded
Coiled-coil. J. Mol. Biol. 383, 854-870 (2008). Kim, E.Y., Rumpf, C.H., Fujiwara, Y., Cooley, E.S., Van Petegem, F., and
Minor, Jr., D.L. Structures of
CaV2 Ca2+/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent
Inactivation and Facilitation. Structure 16, 1455-1467 (2008). Petegem, F.V., Duderstadt, K.E., Clark, K.A., Wang, M., Minor, Jr., D.L., Alanine-Scanning Mutagenesis Defines a Conserved Energetic Hotspot
in the CaVα1 AID-CaVβ Interaction
Site that Is Critical for Channel Modulation. Structure 16,
280-294 (2008) | ||
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| 2007 | ||
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Minor, Jr., D.L., Puzzle
plugged by pore plasticity. Molecular Cell 26 459-460 (2007)
Minor, Jr., D.L., The neurobiologist's guide to structural biology:
A Primer on why macromolecular structure matters and how to evaluate
macromolecular structural data. Neuron 54
511-533 (2007) Howard, R.J., Clark, K.A., Holton, J.M., and Minor, Jr., D.L., Structural
insight into KCNQ (Kv7) channel assembly and channelopathy. Neuron 53
663-675 (2007) | ||
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| 2006 | ||
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Michelsen, K., Mrowiec, T., Duderstadt, K.E., Frey, S., Minor, Jr., D.L.,
Mayer, M.P., Schwappach, B., A multimeric membrane protein reveals 14-3-3
isoform specificity in forward transport in yeast. Traffic 7 903-916 (2006)
Tsuruda, P., Julius, D., and Minor, Jr., D.L., Coiled-coils direct
assembly of a cold-activated TRP channel. Neuron 51
201-212 (2006) Pioletti, M., Findeisen, F., Hura, G.L., and Minor, Jr., D.L., Three-dimensional
structure of the KChIP/Kv4.3 T1 domain complex reveals a cross-shaped octamer. Nature
Structural & Molecular Biology (2006) Minor, Jr., D.L., A sensitive channel family replete
with sense and motion. Nature Structural & Molecular
Biology 13 388-390 (2006) Minor, Jr., D.L., Wanting contact: how to pick up a channel. Nature
Chemical Biology 2 298-299 (2006) Van Petegem, F. and Minor, Jr., D.L., The structural biology of
voltage-gated calcium channel function and regulation. Biochemical
Society Transactions Vol 34, part 5 (2006) |
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| 2005 | ||
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Insights into voltage-gated calcium channel
regulation from the structure of the CaV1.2 IQ domain-Ca2+/calmodulin
complex. The pore helix dipole has a minor role in
inward rectifier channel function. Bend
to open? |
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| 2000-2004 | ||
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Overview: Function and three-dimensional structures
of ion channels. Structure of a complex between a voltage gated calcium channel
beta-subunit and an alpha-subunit domain. The
structure of APPBP-1UBA3-NEDD8-ATP complex reveals the basis for
selective ubiquitin-like protein activation by an E1. Consensus-derived
structural determinants of the ankyrin repeat motif. Potassium
Channels: life in the post-structural world. Controlling
potassium channel activities: Interplay between the membrane and
intracellular factors. The
polar T1 interface is linked to conformational changes that open
the voltage-gated potassium channel. |
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| 1994-1999 | ||
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Transmembrane
structure of an inwardly rectifying potassium channel. Identification
of (D)-peptide ligands through Mirror-Image phage display. Context-dependent
secondary structure formation of a designed protein sequence. Measurement
of the beta-sheet forming propensities of amino acids. Context is a major determinant
of beta-sheet propensity. |
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