Ajay Chawla, M.D., Ph.D


Research Interests:
Immune determinants of metabolism and regeneration; Nuclear receptor signaling in innate immune cells

Across species, the aberrant activation of the innate immune system has been linked to pathogenesis of metabolic, inflammatory and degenerative diseases. However, the molecular pathways by which innate immune cells coordinate these diverse programs remain poorly understood. Our laboratory aims to elucidate the regulatory role of nuclear receptors and co-activator proteins in innate immune activation, and the importance of these pathways in paradigms of health and disease, such as obesity, diabetes, cancer and tissue regeneration.

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