Research Interests:
Regulation of lung and airway function by mast cell, leukocyte and epithelial proteases
Summary:
The Caughey lab is interested in understanding how protein-cleaving enzymes of mast cells, white blood cells, and cells lining the airway contribute to inflammation, host defense, tissue remodeling and barrier function in the lung. These studies relate to clinical problems in asthma, cystic fibrosis, lung transplantation and pneumonia.