Research Interests:
Role of apoptosis in asbestos-induced malignancy. Molecular interaction of asbestos fibers with mesothelial cells, specifically with regard to the role of cell surface adhesion receptors.
Summary:
Our lab studies the ways that tumor cells resist dying either when they are single cells or when they aggregate into clumps, called 3-dimensional spheroids. Our goal is to understand the strategies that resistant tumors use to avoid death and then find ways to bypass these defenses.