Congratulations to Chris and Lijun on publication of their paper in which we present the first crystal structure of a HIPK kinase family member, HIPK2, bound to a small molecule kinase inhibitor. Our structure reveals architecture of the entire kinase domain, the inhibitor-bound active site, and of the CMGC insert region, characteristic for this class of kinases. Our structure opens previously closed doors to design of specific HIPK2 inhibitors and functional exploration of the unique CMGC insert region in HIPK2 signaling. This project was done in collaboration with Dr. David Jablons (UCSF) and Dr. Kannan Natarajan (University of Georgia). The story made the cover of JBC and was described in an editorial in Science Signaling!