Peter Ganz, MD

Ganz2
Professor
Medicine
Faculty Type
Affiliate Faculty

Research Interests: Human endothelial biology, inflammation in cardiovascular diseases, statins, cardiovascular disease in rheumatoid arthritis, cardiovascular disease in HIV, cardiovascular effects of smoking and second hand smoke, cardiovascular effects of air pollutants. Summary: Dr. Ganz' research interests have focused on the role of endothelial dysfunction and inflammation in cardiovascular disease in human subjects. In health, endothelium (the cell lining the inside of arteries), protects against diseases of blood vessels such as atherosclerosis (blockages in arteries). In the presence of damaging risk factors (for example, too much bad cholesterol, not enough good cholesterol, smoking, diabetes or high blood pressure), the endothelium becomes injured and promotes rather than retards cardiovascular disease. The same damaging risk factors also stimulate inflammation in the wall of human arteries. Inflammation and endothelial dysfunction lead to heart attacks and deaths from heart disease; thus, Dr. Ganz is currently focused on finding treatments to reverse endothelial dysfunction and reduce inflammation and their harmful effects and thereby prevent cardiovascular disease in patients.

Publications

Associations of High Attenuation Area-Related Proteomic Biomarkers with Fibrotic or Subpleural Interstitial Lung Abnormalities.

American journal of respiratory and critical care medicine

Kim JS, Debban CL, Guzman DE, Hannan RT, Salvatore M, McGroder C, Zhang D, Podolanczuk AJ, Duprez DA, Ma SF, Huang Y, Sturek JM, Rich SS, Rotter JI, Deo R, Dubin RF, Pugashetti JV, Wang JM, Han MK, Oldham JM, Noth I, Woodruff PG, Ortega VE, Fanburg-Smith JC, Stelow EB, Moskaluk CA, Hoffman EA, Garcia CK, Bowler RP, Ganz P, Barr RG, Manichaikul A

Cross-Ancestry Comparison of Aptamer and Antibody Proteomics Measures.

Research square

Raffield L, Nicholas J, Katz D, Tahir U, Debban C, Aguet F, Blackwell T, Bowler R, Broadaway K, Chen J, Clish C, Coresh J, Cornell E, Cruz D, Deo R, Doyle M, Durda P, Ekunwe L, Floyd J, Gill D, Guo X, Hoogeveen R, Johnson WC, Lange L, Li Y, Manning A, Meigs J, Mi M, Mychaleckyj J, Olson N, Pratte K, Psaty B, Reiner A, Ruan P, Sevilla-Gonzalez M, Shah A, Sun Q, Tracy R, Wen J, Wood A, Wilson J, Young K, Yu B, Rooney M, Manichaikul A, Dubin R, Mohlke K, Rich S, Rotter J, Ganz P, Gerszten R, Taylor K

Human Plasma Proteomic Profile of Clonal Hematopoiesis.

bioRxiv : the preprint server for biology

Yu Z, Vromman A, Nguyen NQH, Schuermans A, Rentz T, Vellarikkal SK, Uddin MM, Niroula A, Griffin G, Honigberg MC, Lin AE, Gibson CJ, Katz DH, Tahir U, Fang S, Haidermota S, Ganesh S, Antoine T, Weinstock J, Austin TR, Ramachandran VS, Peloso GM, Hornsby W, Ganz P, Manson JE, Haring B, Kooperberg CL, Reiner AP, Bis JC, Psaty BM, Min YI, Correa A, Lange LA, Post WS, Rotter JI, Rich SS, Wilson JG, Ebert BL, Yu B, Ballantyne CM, Coresh J, Sankaran VG, Bick AG, Jaiswal S, Gerszten RE, NHLBI Trans-Omics for Precision Medicine, Libby P, Gupta RM, Natarajan P

Association of Integrated Proteomic and Metabolomic Modules with Risk of Kidney Disease Progression.

Journal of the American Society of Nephrology : JASN

Schlosser P, Surapaneni AL, Borisov O, Schmidt IM, Zhou L, Anderson A, Deo R, Dubin R, Ganz P, He J, Kimmel PL, Li H, Nelson RG, Porter AC, Rahman M, Rincon-Choles H, Shah V, Unruh ML, Vasan RS, Zheng Z, Feldman HI, Waikar SS, Köttgen A, Rhee EP, Coresh J, Grams ME, Chronic Renal Insufficiency Cohort (CRIC) Study Investigators and the CKD Biomarkers Consortium

Testican-2 Is Associated with Reduced Risk of Incident ESKD.

Journal of the American Society of Nephrology : JASN

Wen D, Zhou L, Zheng Z, Surapaneni A, Ballantyne CM, Hoogeveen RC, Shlipak MG, Waikar SS, Vasan RS, Kimmel PL, Dubin RF, Deo R, Feldman HI, Ganz P, Coresh J, Grams ME, Rhee EP, CKD Biomarkers Consortium

Plasma protein patterns as comprehensive indicators of health.

Nature medicine

Williams SA, Kivimaki M, Langenberg C, Hingorani AD, Casas JP, Bouchard C, Jonasson C, Sarzynski MA, Shipley MJ, Alexander L, Ash J, Bauer T, Chadwick J, Datta G, DeLisle RK, Hagar Y, Hinterberg M, Ostroff R, Weiss S, Ganz P, Wareham NJ

In Reply.

Menopause (New York, N.Y.)

Huang AJ, Ganz P, Grady D, Cummings SR

Address

2540 23rd Street, Rm 4204
UCSF Box 0846
San Francisco, CA 94110
United States