Randall Lee, MD

Lakkireddy DR, Wilber DJ, Mittal S, Tschopp D, Ellis CR, Rasekh A, Hounshell T, Evonich R, Chandhok S, Berger RD, Horton R, Hoskins MH, Calkins H, Yakubov SJ, Simons P, Saville BR, Lee RJ, aMAZE Investigators

Percutaneous Alginate Hydrogel Endomyocardial Injection with a Novel Dedicated Catheter Delivery System: An Animal Feasibility Study.

Journal of cardiovascular translational research

Wang B, Gao C, Lim S, Wang R, Zhu CJ, Onuma Y, Wang Y, Gao R, Serruys PWJC, Lee RJ, Tao L

Hybrid Endo-Epicardial Therapies for Advanced Atrial Fibrillation.

Journal of clinical medicine

Wong CX, Buch EF, Beygui R, Lee RJ

Acute alcohol exposure and electrocardiographic changes: Finding from the HOLIDAY trial.

Journal of electrocardiology

Ciuffo L, Tung M, Dukes JW, Vittinghoff E, Moss JD, Lee RJ, Lee BK, Tseng ZH, Vedantham V, Olgin JE, Scheinman MM, Hsia H, Ramchandani VA, Gerstenfeld EP, Marcus GM

Postoperative Coagulation Changes in Patients after Epicardial Left Atrial Appendage Occlusion Varies Based on the Left Atrial Appendage Size.

Diseases (Basel, Switzerland)

Batko J, Rusinek J, Slomka A, Litwinowicz R, Burysz M, Bartus M, Lakkireddy DR, Lee RJ, Natorska J, Zabczyk M, Kapelak B, Bartus K

Local decorin delivery via hyaluronic acid microrods improves cardiac performance, ventricular remodeling after myocardial infarction.

NPJ Regenerative medicine

Mohindra P, Zhong JX, Fang Q, Cuylear DL, Huynh C, Qiu H, Gao D, Kharbikar BN, Huang X, Springer ML, Lee RJ, Desai TA

Fibulin-3 is necessary to prevent cardiac rupture following myocardial infarction.

Scientific reports

Murtha LA, Hardy SA, Mabotuwana NS, Bigland MJ, Bailey T, Raguram K, Liu S, Ngo DT, Sverdlov AL, Tomin T, Birner-Gruenberger R, Hume RD, Iismaa SE, Humphreys DT, Patrick R, Chong JJH, Lee RJ, Harvey RP, Graham RM, Rainer PP, Boyle AJ

Endocardial-to-Epicardial Wenckebach Conduction in the Left Atrium: Implications for 3-Dimensional Re-Entry During Atrial Fibrillation.

JACC. Clinical electrophysiology

Wong CX, Howell SJ, Lee RJ

The Strengths and Weaknesses of Left Atrial Appendage Ligation or Exclusion (LARIAT, AtriaClip, Surgical Suture).

Cardiac electrophysiology clinics

Lee RJ, Hanke T

Log-Spectral Matching GAN: PPG-based Atrial Fibrillation Detection can be Enhanced by GAN-based Data Augmentation with Integration of Spectral Loss.

IEEE journal of biomedical and health informatics

Ding C, Xiao R, Do D, Lee DS, Lee RJ, Kalantarian S, Hu X

A Randomized Trial of High vs Standard Power Radiofrequency Ablation for Pulmonary Vein Isolation: SHORT-AF.

JACC. Clinical electrophysiology

Lee AC, Voskoboinik A, Cheung CC, Yogi S, Tseng ZH, Moss JD, Dewland TA, Lee BK, Lee RJ, Hsia HH, Marcus GM, Vedantham V, Chieng D, Kistler PM, Dillon W, Vittinghoff E, Gerstenfeld EP

Hybrid epicardial and endocardial sinus node-sparing ablation therapy for inappropriate sinus tachycardia: Rationale and design of the multicenter HEAL-IST IDE trial.

Heart rhythm O2

de Asmundis C, Pannone L, Lakkireddy D, Beaver TM, Brodt CR, Lee RJ, Frazier K, Chierchia GB, La Meir M

Premature Atrial Contraction Location and Atrial Fibrillation Inducibility.

Circulation. Arrhythmia and electrophysiology

Howell SJ, Dukes JW, Vittinghoff E, Tang JJ, Moss JD, Lee RJ, Lee BK, Tseng ZH, Vedantham V, Olgin JE, Scheinman MM, Hsia H, Gerstenfeld EP, Marcus GM

First-in-human transcatheter endocardial alginate-hydrogel implantation for the treatment of heart failure.

European heart journal

Wang B, Lee RJ, Tao L

Randomized Comparison of a Radiofrequency Wire Versus a Radiofrequency Needle System for Transseptal Puncture.

JACC. Clinical electrophysiology

Dewland TA, Gerstenfeld EP, Moss JD, Lee AC, Vedantham V, Lee RJ, Tseng ZH, Hsia HH, Lee BK, Wall GC, Chang KR, Yang MH, Marcus GM

The Value of Programmed Ventricular Extrastimuli From the Right Ventricular Basal Septum During Supraventricular Tachycardia.

JACC. Clinical electrophysiology

Higuchi S, Ito H, Gerstenfeld EP, Lee AC, Lee BK, Marcus GM, Hsia HH, Moss JD, Lee RJ, Dewland TA, Vedantham V, Tseng ZH, Patel AR, Tanel RE, Badhwar N, Pellegrini CN, Kawamura M, Shoda M, Hwang C, Refaat MM, Scheinman MM

Impact of Label Noise on the Learning Based Models for a Binary Classification of Physiological Signal.

Sensors (Basel, Switzerland)

Ding C, Pereira T, Xiao R, Lee RJ, Hu X

Targeted Treatment of Inappropriate Sinoatrial Node Tachycardia Based on Electrophysiological and Structural Mechanisms.

The American journal of cardiology

de Asmundis C, Pannone L, Lakkireddy D, Beaver TM, Brodt CR, Lee RJ, Sorgente A, Gauthey A, Monaco C, Overeinder I, Bala G, Almorad A, Ströker E, Sieira J, Brugada P, Chierchia GB, La Meir M, Olshansky B

Engineering stem cell therapeutics for cardiac repair.

Journal of molecular and cellular cardiology

Fang J, Li JJ, Zhong X, Zhou Y, Lee RJ, Cheng K, Li S

The Strengths and Weaknesses of Left Atrial Appendage Ligation or Exclusion (LARIAT, AtriaClip, Surgical Suture).

Interventional cardiology clinics

Lee RJ, Hanke T

Long Term Impact of Epicardial Left Atrial Appendage Ligation on Systemic Hemostasis: LAA HOMEOSTASIS-2.

Journal of clinical medicine

Bartus K, Kanuri SH, Litwinowicz R, Ali Elbey M, Natorska J, Zabczyk M, Bartus M, Kapelak B, Gopinnathannair R, Garg J, Turagam MK, Malecki MT, Lee RJ, Lakkireddy D

Acute Consumption of Alcohol and Discrete Atrial Fibrillation Events.

Annals of internal medicine

Marcus GM, Vittinghoff E, Whitman IR, Joyce S, Yang V, Nah G, Gerstenfeld EP, Moss JD, Lee RJ, Lee BK, Tseng ZH, Vedantham V, Olgin JE, Scheinman MM, Hsia H, Gladstone R, Fan S, Lee E, Fang C, Ogomori K, Fatch R, Hahn JA

Epicardial Contrast Injection to Guide Left Atrial Appendage Closure.

HeartRhythm case reports

Dewland TA, Yoruk A, Lee RJ

Unraveling the Gordian Knot!: Hospital Volume Threshold to Optimize Outcomes After Left Atrial Appendage Occlusion.

JACC. Cardiovascular interventions

Moussa ID, Lee RJ

A Randomized, Double-Blind, Placebo-Controlled Trial of Intravenous Alcohol to Assess Changes in Atrial Electrophysiology.

JACC. Clinical electrophysiology

Marcus GM, Dukes JW, Vittinghoff E, Nah G, Badhwar N, Moss JD, Lee RJ, Lee BK, Tseng ZH, Walters TE, Vedantham V, Gladstone R, Fan S, Lee E, Fang C, Ogomori K, Hue T, Olgin JE, Scheinman MM, Hsia H, Ramchandani VA, Gerstenfeld EP

Explainability Metrics of Deep Convolutional Networks for Photoplethysmography Quality Assessment.

IEEE access : practical innovations, open solutions

Zhang O, Ding C, Pereira T, Xiao R, Gadhoumi K, Meisel K, Lee RJ, Chen Y, Hu X

Giant Left Atrium Associated with Massive Thrombus Formation 14 Years after Orthotopic Heart Transplantation.

Brazilian journal of cardiovascular surgery

Bartus K, Litwinowicz R, Kapelak B, Filip G, Wierzbicki K, Lee RJ

Endocardial versus epicardial left atrial appendage exclusion for stroke prevention in patients with atrial fibrillation: Midterm follow-up.

Journal of cardiovascular electrophysiology

Litwinowicz R, Burysz M, Mazur P, Kapelak B, Bartus M, Lakkireddy D, Lee RJ, Malec-Litwinowicz M, Bartus K

Percutaneous epicardial approach for LAA ligation.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

Sanchez JM, Lee A, Bartus K, Lee RJ

Incidence and outcomes of patients with atrial fibrillation and major bleeding complications: from the TREAT-AF study.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

Perino AC, Kaiser DW, Lee RJ, Fan J, Askari M, Schmitt SK, Turakhia MP

Subxiphoid Hybrid Epicardial-Endocardial Atrial Fibrillation Ablation and LAA Ligation: Initial Sub-X Hybrid MAZE Registry Results.

JACC. Clinical electrophysiology

Ellis CR, Badhwar N, Tschopp D, Danter M, Jackson GG, Kerendi F, Walters T, Fang Q, Deuse T, Beygui R, Lee RJ

A collective European experience with left atrial appendage suture ligation using the LARIAT+ device.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

Tilz RR, Fink T, Bartus K, Wong T, Vogler J, Nentwich K, Panniker S, Fang Q, Piorkowski C, Liosis S, Gaspar T, Sawan N, Metzner A, Nietlispach F, Maisano F, Lee RJ, Foran JP, Ouyang F, Sievert H, Deneke T, Kuck KH

Photoplethysmography based atrial fibrillation detection: a review.

NPJ digital medicine

Pereira T, Tran N, Gadhoumi K, Pelter MM, Do DH, Lee RJ, Colorado R, Meisel K, Hu X

Anatomic Considerations for Epicardial and Endocardial Left Atrial Appendage Closure.

Cardiac electrophysiology clinics

Voskoboinik A, Lee RJ

Development of Injectable Amniotic Membrane Matrix for Postmyocardial Infarction Tissue Repair.

Advanced Healthcare Materials

Henry JJD, Delrosario L, Fang J, Wong SY, Fang Q, Sievers R, Kotha S, Wang A, Farmer D, Janaswamy P, Lee RJ, Li S

Coagulation factors and fibrinolytic activity in the left atrial appendage and other heart chambers in patients with atrial fibrillation: is there a local intracardiac prothrombotic state? (HEART-CLOT study).

International journal of cardiology

Bartus K, Litwinowicz R, Natorska J, Zabczyk M, Undas A, Kapelak B, Lakkireddy D, Lee RJ

Reduction in risk of stroke and bleeding after left atrial appendage closure with LARIAT device in patients with increased risk of stroke and bleeding: Long term results.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

Litwinowicz R, Bartus M, Kapelak B, Suwalski P, Lakkireddy D, Lee RJ, Bartus K

Novel role of extracellular matrix protein 1 (ECM1) in cardiac aging and myocardial infarction.

PloS one

Hardy SA, Mabotuwana NS, Murtha LA, Coulter B, Sanchez-Bezanilla S, Al-Omary MS, Senanayake T, Loering S, Starkey M, Lee RJ, Rainer PP, Hansbro PM, Boyle AJ

Enhancement of human adipose-derived stem cell spheroid differentiation in an in situ enzyme-crosslinked gelatin hydrogel.

Journal of materials chemistry. B

Tsai CC, Hong YJ, Lee RJ, Cheng NC, Yu J

Long term outcomes after left atrial appendage closure with the LARIAT device-Stroke risk reduction over five years follow-up.

PloS one

Litwinowicz R, Bartus M, Burysz M, Brzezinski M, Suwalski P, Kapelak B, Vuddanda V, Lakkireddy D, Lee RJ, Trabka R, Bartus K

Rapid left atrial appendage thrombus formation before suture ligation with LARIAT.

Postepy w kardiologii interwencyjnej = Advances in interventional cardiology

Bartus K, Myc J, Bartus M, Lee RJ, Litwinowicz R, Dziewierz A, Kapelak B

Combining Desorption Electrospray Ionization Mass Spectrometry Imaging and Machine Learning for Molecular Recognition of Myocardial Infarction.

Analytical chemistry

Margulis K, Zhou Z, Fang Q, Sievers RE, Lee RJ, Zare RN

An overview of current and emerging devices for percutaneous left atrial appendage closure.

Trends in cardiovascular medicine

Chow DHF, Wong YH, Park JW, Lam YY, De Potter T, Rodés-Cabau J, Asmarats L, Sandri M, Sideris E, McCaw T, Lee RJ, Sievert H, Søndergaard L, De Backer O

Subxiphoid Hybrid Approach for Epicardial/Endocardial Ablation and LAA Exclusion in Patients with Persistent and Longstanding Atrial Fibrillation.

Journal of atrial fibrillation

Badhwar N, Al-Dosari G, Dukes J, Lee RJ

Use of Programmed Ventricular Extrastimulus During Supraventricular Tachycardia to Differentiate Atrioventricular Nodal Re-Entrant Tachycardia From Atrioventricular Re-Entrant Tachycardia.

JACC. Clinical electrophysiology

Ito H, Badhwar N, Patel AR, Hoffmayer KS, Moss JD, Pellegrini CN, Vedantham V, Tseng ZH, Tanel RE, Hsia HH, Lee RJ, Marcus GM, Gerstenfeld EP, Scheinman MM

Injectable hyaluronic acid based microrods provide local micromechanical and biochemical cues to attenuate cardiac fibrosis after myocardial infarction.

Biomaterials

Le LV, Mohindra P, Fang Q, Sievers RE, Mkrtschjan MA, Solis C, Safranek CW, Russell B, Lee RJ, Desai TA

Hybrid and surgical procedures for the treatment of persistent and longstanding persistent atrial fibrillation.

Expert review of cardiovascular therapy

Sanchez JM, Al-Dosari G, Chu S, Beygui R, Deuse T, Badhwar N, Lee RJ

Pericardial Delivery of Biological Agents: The Next Frontier?

JACC. Basic to translational science

Govea A, Lee RJ

Patients With Atrial Fibrillation Who Are Not on Anticoagulant Treatment Due to Increased Bleeding Risk Are Common and Have a High Risk of Stroke.

JACC. Clinical electrophysiology

Redfors B, Gray WA, Lee RJ, Ellenbogen KA, Bonafede M, Ben-Yehuda O

Atrial fibrillation patients with isolated pulmonary veins: Is sinus rhythm achievable?

Journal of cardiovascular electrophysiology

Szilágyi J, Marcus GM, Badhwar N, Lee BK, Lee RJ, Vedantham V, Tseng ZH, Walters T, Scheinman M, Olgin J, Gerstenfeld EP

Aging is protective against pressure overload cardiomyopathy via adaptive extracellular matrix remodeling.

American journal of cardiovascular disease

Geng X, Hwang J, Ye J, Shih H, Coulter B, Naudin C, Jun K, Sievers R, Yeghiazarians Y, Lee RJ, Boyle AJ

The QT Interval as a Noninvasive Marker of Atrial Refractoriness.

Pacing and clinical electrophysiology : PACE

Nguyen KT, Gladstone RA, Dukes JW, Nazer B, Vittinghoff E, Badhwar N, Vedantham V, Gerstenfeld EP, Lee BK, Lee RJ, Tseng ZH, Olgin JE, Scheinman MM, Marcus GM

Conversion of persistent atrial fibrillation to sinus rhythm after LAA ligation with the LARIAT device.

International journal of cardiology

Badhwar N, Mittal S, Rasekh A, Vasaiwala S, Musat D, S Naeini P, Fang Q, Nentwich K, Deneke T, Chang J, Lakkireddy D, Wilber D, Lee RJ

Current Treatment Strategies for Heart Failure: Role of Device Therapy and LV Reconstruction.

Current treatment options in cardiovascular medicine

Janaswamy P, Walters TE, Nazer B, Lee RJ

Clinical Significance of Leaks Following Left Atrial Appendage Ligation With the LARIAT Suture Delivery Device.

JACC. Cardiovascular interventions

Lee RJ

Left atrial appendage ligation with the next generation LARIAT(+) suture delivery device: Early clinical experience.

International journal of cardiology

Bartus K, Gafoor S, Tschopp D, Foran JP, Tilz R, Wong T, Lakkireddy D, Sievert H, Lee RJ

Short and long-term outcomes of percutaneous left atrial appendage suture ligation: Results from a US multicenter evaluation.

Heart rhythm

Lakkireddy D, Afzal MR, Lee RJ, Nagaraj H, Tschopp D, Gidney B, Ellis C, Altman E, Lee B, Kar S, Bhadwar N, Sanchez M, Gadiyaram V, Evonich R, Rasekh A, Cheng J, Cuoco F, Chandhok S, Gunda S, Reddy M, Atkins D, Bommana S, Cuculich P, Gibson D, Nath J, Ferrell R, Matthew E, Wilber D

Impact of Periprocedural Colchicine on Postprocedural Management in Patients Undergoing a Left Atrial Appendage Ligation Using LARIAT.

Journal of cardiovascular electrophysiology

Gunda S, Reddy M, Nath J, Nagaraj H, Atoui M, Rasekh A, Ellis CR, Badhwar N, Lee RJ, DI Biase L, Mansour M, Ruskin JN, Natale A, Earnest M, Lakkireddy DR

Reversible High-Grade Atrioventricular Block Associated With Cocaine Use.

JAMA internal medicine

Hall PS, Nazer B, Lee RJ

One-year follow-up results from AUGMENT-HF: a multicentre randomized controlled clinical trial of the efficacy of left ventricular augmentation with Algisyl in the treatment of heart failure.

European journal of heart failure

Mann DL, Lee RJ, Coats AJ, Neagoe G, Dragomir D, Pusineri E, Piredda M, Bettari L, Kirwan BA, Dowling R, Volterrani M, Solomon SD, Sabbah HN, Hinson A, Anker SD

Left Atrial Appendage Ligation in Nonvalvular Atrial Fibrillation Patients at High Risk for Embolic Events With Ineligibility for Oral Anticoagulation: Initial Report of Clinical Outcomes.

JACC. Clinical electrophysiology

Sievert H, Rasekh A, Bartus K, Morelli RL, Fang Q, Kuropka J, Le D, Gafoor S, Heuer L, Safavi-Naeini P, Hue TF, Marcus GM, Badhwar N, Massumi A, Lee RJ

Percutaneous alternative to the Maze procedure for the treatment of persistent or long-standing persistent atrial fibrillation (aMAZE trial): Rationale and design.

American heart journal

Lee RJ, Lakkireddy D, Mittal S, Ellis C, Connor JT, Saville BR, Wilber D

The Effect of Direct Current Stimulation versus T-Wave Shock on Defibrillation Threshold Testing.

Pacing and clinical electrophysiology : PACE

Ito H, Kawamura M, Badhwar N, Vedantham V, Tseng ZH, Lee BK, Lee RJ, Marcus GM, Gerstenfeld EP, Scheinman MM

The feasibility and safety of Algisyl-LVR™ as a method of left ventricular augmentation in patients with dilated cardiomyopathy: initial first in man clinical results.

International journal of cardiology

Lee RJ, Hinson A, Bauernschmitt R, Matschke K, Fang Q, Mann DL, Dowling R, Schiller N, Sabbah HN

A prospective comparison of alginate-hydrogel with standard medical therapy to determine impact on functional capacity and clinical outcomes in patients with advanced heart failure (AUGMENT-HF trial).

European heart journal

Anker SD, Coats AJ, Cristian G, Dragomir D, Pusineri E, Piredda M, Bettari L, Dowling R, Volterrani M, Kirwan BA, Filippatos G, Mas JL, Danchin N, Solomon SD, Lee RJ, Ahmann F, Hinson A, Sabbah HN, Mann DL

Left atrial appendage occlusion for stroke prevention in patients with atrial fibrillation.

Expert review of cardiovascular therapy

Le D, Morelli R, Badhwar N, Lee RJ

Left atrial appendage ligation in patients with atrial fibrillation leads to a decrease in atrial dispersion.

Journal of the American Heart Association

Kawamura M, Scheinman MM, Lee RJ, Badhwar N

Sequential Percutaneous LAA Ligation and Pulmonary Vein Isolation in Patients with Persistent AF: Initial Results of a Feasibility Study.

Journal of cardiovascular electrophysiology

Badhwar N, Lakkireddy D, Kawamura M, Han FT, Iyer SK, Moyers BS, Dewland TA, Woods C, Ferrell R, Nath J, Earnest M, Lee RJ

Immuno-modification of enhancing stem cells targeting for myocardial repair.

Journal of cellular and molecular medicine

Yu J, Wu YK, Gu Y, Fang Q, Sievers R, Ding CH, Olgin JE, Lee RJ

Delivery of lipid micelles into infarcted myocardium using a lipid-linked matrix metalloproteinase targeting peptide.

Molecular pharmaceutics

Nguyen J, Sievers R, Motion JP, Kivimäe S, Fang Q, Lee RJ

Surgical and concomitant epicardial-endocardial (hybrid) ablation of persistent and long-standing persistent atrial fibrillation.

Current problems in cardiology

Badhwar N, Tschopp DR, Lee RJ

Impact of left atrial appendage exclusion using an epicardial ligation system (LARIAT) on atrial fibrillation burden in patients with cardiac implantable electronic devices.

Heart rhythm

Afzal MR, Kanmanthareddy A, Earnest M, Reddy M, Atkins D, Bommana S, Bartus K, Rasekh A, Han F, Badhwar N, Cheng J, Dibiase L, Ellis CR, Dawn B, Natale A, Lee RJ, Lakkireddy D

Anatomic analysis of the left atrial appendage after closure with the LARIAT device.

Circulation. Arrhythmia and electrophysiology

Bartus K, Morelli RL, Szczepanski W, Kapelak B, Sadowski J, Lee RJ

Discrete microstructural cues for the attenuation of fibrosis following myocardial infarction.

Biomaterials

Pinney JR, Du KT, Ayala P, Fang Q, Sievers RE, Chew P, Delrosario L, Lee RJ, Desai TA

Evolution of stroke prevention in nonvalvular atrial fibrillation patients.

Journal of the American College of Cardiology

Lee RJ

His overdrive pacing during supraventricular tachycardia: a novel maneuver for distinguishing atrioventricular nodal reentrant tachycardia from atrioventricular reciprocating tachycardia.

Heart rhythm

Singh DK, Viswanathan MN, Tanel RE, Lee RJ, Lee BK, Marcus GM, Olgin JE, Han F, Vedantham V, Tseng ZH, Pellegrini C, Kawamura M, Gerstenfeld EP, Badhwar N, Scheinman M

Coupling interval dispersion and body mass index are independent predictors of idiopathic premature ventricular complex-induced cardiomyopathy.

Journal of cardiovascular electrophysiology

Kawamura M, Badhwar N, Vedantham V, Tseng ZH, Lee BK, Lee RJ, Marcus GM, Olgin JE, Gerstenfeld EP, Scheinman MM

Safety of new oral anticoagulants for patients undergoing atrial fibrillation ablation.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

Stepanyan G, Badhwar N, Lee RJ, Marcus GM, Lee BK, Tseng ZH, Vedantham V, Olgin J, Scheinman M, Gerstenfeld EP

LAA ligation using the LARIAT suture delivery device: tips and tricks for a successful procedure.

Heart rhythm

Koneru JN, Badhwar N, Ellenbogen KA, Lee RJ

The effects of LAA ligation on LAA electrical activity.

Heart rhythm

Han FT, Bartus K, Lakkireddy D, Rojas F, Bednarek J, Kapelak B, Bartus M, Sadowski J, Badhwar N, Earnest M, Valderrabano M, Lee RJ

The effects of aging on apoptosis following myocardial infarction.

Cardiovascular therapeutics

Boyle AJ, Hwang J, Ye J, Shih H, Jun K, Zhang Y, Fang Q, Sievers R, Yeghiazarians Y, Lee RJ

Aging Impairs the Proliferative Capacity of Cardiospheres, Cardiac Progenitor Cells and Cardiac Fibroblasts: Implications for Cell Therapy.

Journal of clinical medicine

Ye J, Hom DS, Hwang J, Yeghiazarians Y, Lee RJ, Boyle AJ

Randomized trial of conventional transseptal needle versus radiofrequency energy needle puncture for left atrial access (the TRAVERSE-LA study).

Journal of the American Heart Association

Hsu JC, Badhwar N, Gerstenfeld EP, Lee RJ, Mandyam MC, Dewland TA, Imburgia KE, Hoffmayer KS, Vedantham V, Lee BK, Tseng ZH, Scheinman MM, Olgin JE, Marcus GM

Shox2 regulates the pacemaker gene program in embryoid bodies.

Stem cells and development

Hashem SI, Lam ML, Mihardja SS, White SM, Lee RJ, Claycomb WC

The effect of a peptide-modified thermo-reversible methylcellulose on wound healing and LV function in a chronic myocardial infarction rodent model.

Biomaterials

Mihardja SS, Gonzales JA, Gao D, Sievers RE, Fang Q, Stillson CA, Yu J, Peng M, Lee RJ

Augmentation of left ventricular wall thickness with alginate hydrogel implants improves left ventricular function and prevents progressive remodeling in dogs with chronic heart failure.

JACC. Heart failure

Sabbah HN, Wang M, Gupta RC, Rastogi S, Ilsar I, Sabbah MS, Kohli S, Helgerson S, Lee RJ

Pleiotrophin gene therapy for peripheral ischemia: evaluation of full-length and truncated gene variants.

PloS one

Fang Q, Mok PY, Thomas AE, Haddad DJ, Saini SA, Clifford BT, Kapasi NK, Danforth OM, Usui M, Ye W, Luu E, Sharma R, Bartel MJ, Pathmanabhan JA, Ang AA, Sievers RE, Lee RJ, Springer ML

Algisyl-LVR™ with coronary artery bypass grafting reduces left ventricular wall stress and improves function in the failing human heart.

International journal of cardiology

Lee LC, Wall ST, Klepach D, Ge L, Zhang Z, Lee RJ, Hinson A, Gorman JH, Gorman RC, Guccione JM

Percutaneous left atrial appendage suture ligation using the LARIAT device in patients with atrial fibrillation: initial clinical experience.

Journal of the American College of Cardiology

Bartus K, Han FT, Bednarek J, Myc J, Kapelak B, Sadowski J, Lelakowski J, Bartus S, Yakubov SJ, Lee RJ

Using extracellular matrix-derived peptides to alter the microenvironment for myocardial repair.

Current vascular pharmacology

Mihardja SS, Lee RJ

Alcohol and vagal tone as triggers for paroxysmal atrial fibrillation.

The American journal of cardiology

Mandyam MC, Vedantham V, Scheinman MM, Tseng ZH, Badhwar N, Lee BK, Lee RJ, Gerstenfeld EP, Olgin JE, Marcus GM

Polymer-based restoration of left ventricular mechanics.

Cell transplantation

Lee RJ, Hinson A, Helgerson S, Bauernschmitt R, Sabbah HN

Predictors of axillary vein location for vascular access during pacemaker and defibrillator lead implantation.

Pacing and clinical electrophysiology : PACE

Hsu JC, Friday J, Lee BK, Azadani PN, Lee RJ, Badhwar N, Tseng ZH, Olgin JE, Marcus GM

Predictors of unusual ECG characteristics in cavotricuspid isthmus-dependent atrial flutter ablation.

Pacing and clinical electrophysiology : PACE

Hoffmayer KS, Yang Y, Joseph S, McCabe JM, Bhave P, Hsu J, Ng RK, Lee BK, Badhwar N, Lee RJ, Tseng ZH, Olgin JE, Narayan SM, Marcus GM, Scheinman MM

Electrophysiologic properties of para-Hisian atrial tachycardia.

Heart rhythm

Iwai S, Badhwar N, Markowitz SM, Stambler BS, Keung E, Lee RJ, Chung JH, Olgin JE, Scheinman MM, Lerman BB

Extracellular matrix-derived peptides and myocardial repair.

Cell adhesion & migration

Mihardja SS, Yu J, Lee RJ

An engineered cardiac reporter cell line identifies human embryonic stem cell-derived myocardial precursors.

PloS one

Ritner C, Wong SS, King FW, Mihardja SS, Liszewski W, Erle DJ, Lee RJ, Bernstein HS

The aging heart and post-infarction left ventricular remodeling.

Journal of the American College of Cardiology

Shih H, Lee B, Lee RJ, Boyle AJ

Proteomic identification of biomarkers of vascular injury.

American journal of translational research

Huang NF, Kurpinski K, Fang Q, Lee RJ, Li S

Feasibility of closed-chest ligation of the left atrial appendage in humans.

Heart rhythm

Bartus K, Bednarek J, Myc J, Kapelak B, Sadowski J, Lelakowski J, Yakubov SJ, Lee RJ

Prospective observations in the clinical and electrophysiological characteristics of intra-isthmus reentry.

Journal of cardiovascular electrophysiology

Yang Y, Varma N, Badhwar N, Tanel RE, Sundara S, Lee RJ, Lee BK, Tseng ZH, Marcus GM, Kim AM, Olgin JE, Scheinman MM

The use of human mesenchymal stem cells encapsulated in RGD modified alginate microspheres in the repair of myocardial infarction in the rat.

Biomaterials

Yu J, Du KT, Fang Q, Gu Y, Mihardja SS, Sievers RE, Wu JC, Lee RJ

Biophysical and chemical effects of fibrin on mesenchymal stromal cell gene expression.

Acta biomaterialia

Huang NF, Chu J, Lee RJ, Li S

Catheter-based left atrial appendage (LAA) ligation for the prevention of embolic events arising from the LAA: initial experience in a canine model.

Circulation. Cardiovascular interventions

Lee RJ, Bartus K, Yakubov SJ

Targeted in vivo extracellular matrix formation promotes neovascularization in a rodent model of myocardial infarction.

PloS one

Mihardja SS, Gao D, Sievers RE, Fang Q, Feng J, Wang J, Vanbrocklin HF, Larrick JW, Huang M, Dae M, Lee RJ

High-resolution optical mapping of ventricular tachycardia in rats with chronic myocardial infarction.

Pacing and clinical electrophysiology : PACE

Ding C, Gepstein L, Nguyen DT, Wilson E, Hulley G, Beaser A, Lee RJ, Olgin J

Engineering of aligned skeletal muscle by micropatterning.

American journal of translational research

Huang NF, Lee RJ, Li S

Stem cells for myocardial repair and regeneration: where are we today?

Methods in molecular biology (Clifton, N.J.)

Lee RJ

Intracardiac and extracardiac markers of inflammation during atrial fibrillation.

Heart rhythm

Marcus GM, Smith LM, Ordovas K, Scheinman MM, Kim AM, Badhwar N, Lee RJ, Tseng ZH, Lee BK, Olgin JE

Differences in accessory pathway location by sex and race.

Heart rhythm

Hsu JC, Tanel RE, Lee BK, Scheinman MM, Badhwar N, Lee RJ, Tseng ZH, Olgin JE, Marcus GM

Test characteristics of neck fullness and witnessed neck pulsations in the diagnosis of typical AV nodal reentrant tachycardia.

Clinical cardiology

Sakhuja R, Smith LM, Tseng ZH, Badhwar N, Lee BK, Lee RJ, Scheinman MM, Olgin JE, Marcus GM

Bone marrow-derived mesenchymal stem cells in fibrin augment angiogenesis in the chronically infarcted myocardium.

Regenerative medicine

Huang NF, Lam A, Fang Q, Sievers RE, Li S, Lee RJ

Comparison of gene-transfer efficiency in human embryonic stem cells.

Molecular imaging and biology

Cao F, Xie X, Gollan T, Zhao L, Narsinh K, Lee RJ, Wu JC

Remote navigation guided ablation of incessant atrial tachycardia in a patient with restricted venous access.

Journal of cardiovascular electrophysiology

Kim AM, Badhwar N, Lee RJ

Restoration of left ventricular geometry and improvement of left ventricular function in a rodent model of chronic ischemic cardiomyopathy.

The Journal of thoracic and cardiovascular surgery

Yu J, Christman KL, Chin E, Sievers RE, Saeed M, Lee RJ

The effect of injected RGD modified alginate on angiogenesis and left ventricular function in a chronic rat infarct model.

Biomaterials

Yu J, Gu Y, Du KT, Mihardja S, Sievers RE, Lee RJ

Impact of remote magnetic catheter navigation on ablation fluoroscopy and procedure time.

Pacing and clinical electrophysiology : PACE

Kim AM, Turakhia M, Lu J, Badhwar N, Lee BK, Lee RJ, Marcus GM, Tseng ZH, Scheinman M, Olgin JE

Protracted CRP elevation after atrial fibrillation ablation.

Pacing and clinical electrophysiology : PACE

McCabe JM, Smith LM, Tseng ZH, Badhwar N, Lee BK, Lee RJ, Scheinman MM, Olgin JE, Marcus GM

The effect of polypyrrole on arteriogenesis in an acute rat infarct model.

Biomaterials

Mihardja SS, Sievers RE, Lee RJ

Pleiotrophin induces nitric oxide dependent migration of endothelial progenitor cells.

Journal of cellular physiology

Heiss C, Wong ML, Block VI, Lao D, Real WM, Yeghiazarians Y, Lee RJ, Springer ML

Alcohol intake is significantly associated with atrial flutter in patients under 60 years of age and a shorter right atrial effective refractory period.

Pacing and clinical electrophysiology : PACE

Marcus GM, Smith LM, Whiteman D, Tseng ZH, Badhwar N, Lee BK, Lee RJ, Scheinman MM, Olgin JE

Targeting human CD34+ hematopoietic stem cells with anti-CD45 x anti-myosin light-chain bispecific antibody preserves cardiac function in myocardial infarction.

Journal of applied physiology (Bethesda, Md. : 1985)

Zhao TC, Tseng A, Yano N, Tseng Y, Davol PA, Lee RJ, Lum LG, Padbury JF

A first-degree family history in lone atrial fibrillation patients.

Heart rhythm

Marcus GM, Smith LM, Vittinghoff E, Tseng ZH, Badhwar N, Lee BK, Lee RJ, Scheinman MM, Olgin JE

Markers of inflammation before and after curative ablation of atrial flutter.

Heart rhythm

Marcus GM, Smith LM, Glidden DV, Wilson E, McCabe JM, Whiteman D, Tseng ZH, Badhwar N, Lee BK, Lee RJ, Scheinman MM, Olgin JE

Tissue engineering and stem cell therapy for myocardial repair.

Frontiers in bioscience : a journal and virtual library

Gu Y, Yu J, Lum LG, Lee RJ

Chemical and physical regulation of stem cells and progenitor cells: potential for cardiovascular tissue engineering.

Tissue engineering

Huang NF, Lee RJ, Li S

Myocardial infarct size measurement in the mouse chronic infarction model: comparison of area- and length-based approaches.

Journal of applied physiology (Bethesda, Md. : 1985)

Takagawa J, Zhang Y, Wong ML, Sievers RE, Kapasi NK, Wang Y, Yeghiazarians Y, Lee RJ, Grossman W, Springer ML

Antibody targeting of stem cells to infarcted myocardium.

Stem cells (Dayton, Ohio)

Lee RJ, Fang Q, Davol PA, Gu Y, Sievers RE, Grabert RC, Gall JM, Tsang E, Yee MS, Fok H, Huang NF, Padbury JF, Larrick JW, Lum LG

Repeat transseptal catheterization after ablation for atrial fibrillation.

Journal of cardiovascular electrophysiology

Marcus GM, Ren X, Tseng ZH, Badhwar N, Lee BK, Lee RJ, Foster E, Olgin JE

Regional left atrial voltage in patients with atrial fibrillation.

Heart rhythm

Marcus GM, Yang Y, Varosy PD, Ordovas K, Tseng ZH, Badhwar N, Lee BK, Lee RJ, Scheinman MM, Olgin JE

Histologic assessment of right atrial appendage myocardium in patients with atrial fibrillation after coronary artery bypass graft surgery.

Cardiology

Nakai T, Chandy J, Nakai K, Bellows WH, Flachsbart K, Lee RJ, Leung JM

Biomaterials for the treatment of myocardial infarction.

Journal of the American College of Cardiology

Christman KL, Lee RJ

MR guidance of targeted injections into border and core of scarred myocardium in pigs.

Radiology

Saeed M, Martin AJ, Lee RJ, Weber O, Revel D, Saloner D, Higgins CB

Myotube assembly on nanofibrous and micropatterned polymers.

Nano letters

Huang NF, Patel S, Thakar RG, Wu J, Hsiao BS, Chu B, Lee RJ, Li S

A rodent model of myocardial infarction for testing the efficacy of cells and polymers for myocardial reconstruction.

Nature protocols

Huang NF, Sievers RE, Park JS, Fang Q, Li S, Lee RJ

The new face of bispecific antibodies: targeting cancer and much more.

Experimental hematology

Lum LG, Davol PA, Lee RJ

Scarred myocardium imposes additional burden on remote viable myocardium despite a reduction in the extent of area with late contrast MR enhancement.

European radiology

Saeed M, Lee RJ, Weber O, Do L, Martin A, Ursell P, Saloner D, Higgins CB

Injectable biopolymers enhance angiogenesis after myocardial infarction.

Tissue engineering

Huang NF, Yu J, Sievers R, Li S, Lee RJ

Atrial tachycardia arising from the coronary sinus musculature: electrophysiological characteristics and long-term outcomes of radiofrequency ablation.

Journal of the American College of Cardiology

Badhwar N, Kalman JM, Sparks PB, Kistler PM, Attari M, Berger M, Lee RJ, Sra J, Scheinman MM

Virtual reality of stem cell transplantation to repair injured myocardium.

Journal of cellular biochemistry

Lum LG, Padbury JF, Davol PA, Lee RJ

Pleiotrophin induces formation of functional neovasculature in vivo.

Biochemical and biophysical research communications

Christman KL, Fang Q, Kim AJ, Sievers RE, Fok HH, Candia AF, Colley KJ, Herradon G, Ezquerra L, Deuel TF, Lee RJ

Protected circumferential conduction in the posterior atrioventricular vestibule of the left atrium: electrophysiologic and anatomic correlates.

Pacing and clinical electrophysiology : PACE

Cheng J, Yang Y, Ursell PC, Lee RJ, Dorostkar PC, Boahene KA, Scheinman MM

Enhanced neovasculature formation in ischemic myocardium following delivery of pleiotrophin plasmid in a biopolymer.

Biomaterials

Christman KL, Fang Q, Yee MS, Johnson KR, Sievers RE, Lee RJ

Injectable fibrin scaffold improves cell transplant survival, reduces infarct expansion, and induces neovasculature formation in ischemic myocardium.

Journal of the American College of Cardiology

Christman KL, Vardanian AJ, Fang Q, Sievers RE, Fok HH, Lee RJ

Fibrin glue alone and skeletal myoblasts in a fibrin scaffold preserve cardiac function after myocardial infarction.

Tissue engineering

Christman KL, Fok HH, Sievers RE, Fang Q, Lee RJ

Usefulness of a ventricular extrastimulus from the summit of the ventricular septum in diagnosis of septal accessory pathway in patients with supraventricular tachycardia.

The American journal of cardiology

Matsushita T, Badhwar N, Collins KK, Van Hare GF, Barbato G, Lee BK, Lee RJ, Scheinman MM

Comparative effects of aspirin with ACE inhibitor or angiotensin receptor blocker on myocardial infarction and vascular function.

Journal of the renin-angiotensin-aldosterone system : JRAAS

Zhu BQ, Sievers RE, Browne AE, Lee RJ, Chatterjee K, Grossman W, Karliner JS, Parmley WW

Postresuscitation stunning: postfibrillatory myocardial dysfunction caused by reduced myofilament Ca2+ responsiveness after ventricular fibrillation-induced myocyte Ca2+ overload.

Journal of cardiovascular electrophysiology

Zaugg CE, Ziegler A, Lee RJ, Barbosa V, Buser PT

Percutaneous left atrial appendage occlusion (PLAATO) for preventing cardioembolism: first experience in canine model.

Circulation

Nakai T, Lesh MD, Gerstenfeld EP, Virmani R, Jones R, Lee RJ

The renin-angiotensin system does not contribute to the endothelial dysfunction and increased infarct size in rats exposed to second hand smoke.

Journal of the renin-angiotensin-aldosterone system : JRAAS

Zhu BQ, Sievers RE, Browne AE, Hillman RT, Chair K, Lee RJ, Chatterjee K, Glantz SA, Parmley WW

The relative importance of left atrial function versus dimension in predicting atrial fibrillation after coronary artery bypass graft surgery.

American heart journal

Nakai T, Lee RJ, Schiller NB, Bellows WH, Dzankic S, Reeves J, Romson J, Ferguson S, Leung JM

Publications