Joanne Engel, MD, PhD

Engel
Professor
M_MED-CORE-INFD
Faculty Type
Affiliate Faculty

Research Interests: Bacterial Pathogen-Host Cell Interactions Summary: My laboratory is interested understanding and exploiting the complex interplay of microbial pathogens with eukaryotic cells. To that end, we have investigated the key processes of microbial attachment and entry, intracellular survival, and host cell injury in the context of two important human pathogens, Pseudomonas aeruginosa (PA) and Chlamydia trachomatis (CT). Each of these microorganisms has developed a unique strategy for successful survival that involves subverting and exploiting host cell pathways. Dissecting these processes will allow the development of new diagnostics, therapeutics, and vaccines and will provide a unique window into eukaryotic cell biology. 

Publications

Implementation and outcomes of a rapid response genomic hospital epidemiology programme at an academic medical centre over 7 years.

The Lancet. Microbe

Chu VT, Spottiswoode N, Ward R, Yokoe DS, Ramirez-Avila L, Phelps MS, Glascock A, Crawford ED, Kamm J, Hao S, Li L, Dynerman D, Waltari E, Nafees S, Kalantar KL, Caldera S, Madera S, Guerrero ES, Ivashin D, Serpa PH, Love C, Mwakibete LL, Doernberg SB, Kistler A, Alvino R, Engel J, Chiu CY, Pak C, Cunningham G, Reyes H, Buie B, Messacar K, Leroue M, Prince BC, Detweiler AM, Stanley K, Caughell C, McNeil N, Neff N, Nichols A, Miller S, DeRisi JL, Tato CM, Langelier CR

Address

513 Parnassus Avenue HSE, Rm 405
UCSF Box 0654
San Francisco, CA 94143
United States