Holly Ingraham, PhD

Professor, Cellular Molecular Pharmacology

Research Interests: Summary: Our research is focused on development of endocrine and brain regions that contribute to energy balance and reproduction. We concentrate on NR5A nuclear hormone receptors that specify cell fate in developing endocrine organs and the hypothalamus using structural biology, biochemistry and physiology.

Address: 
1550 Fourth Street, Rm 284F
UCSF Box 2611
San Francisco, CA 94158
United States
Phone: 
+1 415 476-3401
Faculty Type: 
Affiliate Faculty
Publications: 

A maternal brain hormone that builds bone.(link is external)

Nature

Babey ME, Krause WC, Chen K, Herber CB, Torok Z, Nikkanen J, Rodriguez R, Zhang X, Castro-Navarro F, Wang Y, Wheeler EE, Villeda S, Leach JK, Lane NE, Scheller EL, Chan CKF, Ambrosi TH, Ingraham HA

Brain-Derived CCN3 Is An Osteoanabolic Hormone That Sustains Bone in Lactating Females.(link is external)

bioRxiv : the preprint server for biology

Babey ME, Krause WC, Herber CB, Chen K, Nikkanen J, Rodriquez R, Zhang X, Castro-Navarro F, Wang Y, Villeda S, Lane NE, Scheller EL, Chan CKF, Ambrosi TH, Ingraham HA

Gut enterochromaffin cells drive visceral pain and anxiety.(link is external)

Nature

Bayrer JR, Castro J, Venkataraman A, Touhara KK, Rossen ND, Morrie RD, Maddern J, Hendry A, Braverman KN, Garcia-Caraballo S, Schober G, Brizuela M, Castro Navarro FM, Bueno-Silva C, Ingraham HA, Brierley SM, Julius D

An evolutionary trade-off between host immunity and metabolism drives fatty liver in male mice.(link is external)

Science (New York, N.Y.)

Nikkanen J, Leong YA, Krause WC, Dermadi D, Maschek JA, Van Ry T, Cox JE, Weiss EJ, Gokcumen O, Chawla A, Ingraham HA

Oestrogen engages brain MC4R signalling to drive physical activity in female mice.(link is external)

Nature

Krause WC, Rodriguez R, Gegenhuber B, Matharu N, Rodriguez AN, Padilla-Roger AM, Toma K, Herber CB, Correa SM, Duan X, Ahituv N, Tollkuhn J, Ingraham HA

Chronic Stimulation of Arcuate Kiss1 Neurons Decreases Bone Mass in Female Mice.

Journal of the Endocrine Society

Ruben Rodriguez, Candice B Herber, William C Krause, Holly A Ingraham

SPARC - Mapping Gut-Spinal Cord Connections in Visceral Pain.

The FASEB Journal

Ryan David Morrie, James Bayrer, Stuart Brierley, Holly Ingraham, David Julius

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