
Assistant Professor
Cardiovascular Research Institute
Research Interests
Inflammatory Mechanisms in Atherosclerosis
Email
+1 415 514-8082
Faculty Type
Core CVRI Faculty
Publications
Aggressive Cholesterol Lowering Normalizes Atherosclerosis Regression in Jak2V617F Clonal Hematopoiesis.
bioRxiv : the preprint server for biology
IL-18 inhibition enlarges lesions, necrotic cores and thickens fibrous caps in Jak2 V617F clonal hematopoiesis-driven atherosclerosis.
bioRxiv : the preprint server for biology
An epigenetic switch in macrophages promotes fibrosis in the failing heart.
Nature Cardiovascular Research
Suppression of IL-1β promotes beneficial accumulation of fibroblast-like cells in atherosclerotic plaques in clonal hematopoiesis.
Nature Cardiovascular Research
Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk.
The Journal of clinical investigation
Endogenous SOD2 (Superoxide Dismutase) Regulates Platelet-Dependent Thrombin Generation and Thrombosis During Aging.
Arteriosclerosis, thrombosis, and vascular biology
Erythroid lineage Jak2V617F expression promotes atherosclerosis through erythrophagocytosis and macrophage ferroptosis.
The Journal of clinical investigation
Modulation of the NLRP3 inflammasome by Sars-CoV-2 Envelope protein.
Scientific reports
Oxidized Phospholipids Promote NETosis and Arterial Thrombosis in LNK(SH2B3) Deficiency.
Circulation
Inhibition of JAK2 Suppresses Myelopoiesis and Atherosclerosis in Apoe-/- Mice.
Cardiovascular drugs and therapy
Loss of MCU prevents mitochondrial fusion in G1-S phase and blocks cell cycle progression and proliferation.
Science signaling
Glucose Metabolism Is Required for Platelet Hyperactivation in a Murine Model of Type 1 Diabetes.
Diabetes
Macrophage Inflammation, Erythrophagocytosis, and Accelerated Atherosclerosis in Jak2 V617F Mice.
Circulation research
Deletion of GLUT1 and GLUT3 Reveals Multiple Roles for Glucose Metabolism in Platelet and Megakaryocyte Function.
Cell reports
Deletion of GLUT1 and GLUT3 Reveals Multiple Roles for Glucose Metabolism in Platelet and Megakaryocyte Function.
Cell reports
Superoxide Dismutase 2 is dispensable for platelet function.
Thrombosis and haemostasis
Deletion of GLUT1 and GLUT3 Reveals Multiple Roles for Glucose Metabolism in Platelet and Megakaryocyte Function.
Cell reports
Erratum: SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis.
Nature cell biology
Glucose Transporter 3 Potentiates Degranulation and Is Required for Platelet Activation.
Arteriosclerosis, thrombosis, and vascular biology
Erratum: SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis.
Nature cell biology
SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis.
Nature cell biology
Metabolic pathways of inhaled glucocorticoids by the CYP3A enzymes.
Drug metabolism and disposition: the biological fate of chemicals
Cytochrome P450 2S1 depletion enhances cell proliferation and migration in bronchial epithelial cells, in part, through modulation of prostaglandin E(2) synthesis.
Drug metabolism and disposition: the biological fate of chemicals
Correction to "improved coiled-coil design enhances interaction with bcr-abl and induces apoptosis".
Molecular pharmaceutics
Improved coiled-coil design enhances interaction with Bcr-Abl and induces apoptosis.
Molecular pharmaceutics
Address
555 & 535 Mission Bay Blvd Sou, Rm 452J
UCSF Box 3122
San Francisco, CA 94158
United States