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RNA-binding proteins and glycoRNAs form domains on the cell surface for cell-penetrating peptide entry.

Cell

Perr J, Langen A, Almahayni K, Nestola G, Chai P, Lebedenko CG, Volk RF, Detrés D, Caldwell RM, Spiekermann M, Hemberger H, Bisaria N, Aiba T, Sánchez-Rivera FJ, Tzelepis K, Calo E, Möckl L, Zaro BW, Flynn RA

HypoxyStat, a small-molecule form of hypoxia therapy that increases oxygen-hemoglobin affinity.

Cell

Blume SY, Garg A, Martí-Mateos Y, Midha AD, Chew BTL, Lin B, Yu C, Dick R, Lee PS, Situ E, Sarwaikar R, Green E, Ramanan V, Grotenbreg G, Hoek M, Sinz C, Jain IH

Synthetic organizer cells guide development via spatial and biochemical instructions.

Cell

Yamada T, Trentesaux C, Brunger JM, Xiao Y, Stevens AJ, Martyn I, Kasparek P, Shroff NP, Aguilar A, Bruneau BG, Boffelli D, Klein OD, Lim WA

A Genome-Wide Screen Identifies the Evolutionarily Conserved KEOPS Complex as a Telomere Regulator.

Cell

Michael Downey, Rebecca Houlsworth, Laura Maringele, Adrienne Rollie, Marc Brehme, Sarah Galicia, Sandrine Guillard, Melanie Partington, Mikhajlo K. Zubko, Nevan J. Krogan, Andrew Emili, Jack F. Greenblatt, Lea Harrington, David Lydall, Daniel Durocher

The single-molecule accessibility landscape of newly replicated mammalian chromatin.

Cell

Ostrowski MS, Yang MG, McNally CP, Abdulhay NJ, Wang S, Renduchintala K, Irkliyenko I, Biran A, Chew BTL, Midha AD, Wong EV, Sandoval J, Jain IH, Groth A, Nora EP, Goodarzi H, Ramani V

Targeting Ras-, Rho-, and Rab-family GTPases via a conserved cryptic pocket.

Cell

Morstein J, Bowcut V, Fernando M, Yang Y, Zhu L, Jenkins ML, Evans JT, Guiley KZ, Peacock DM, Krahnke S, Lin Z, Taran KA, Huang BJ, Stephen AG, Burke JE, Lightstone FC, Shokat KM

Opposing GPCR signaling programs protein intake setpoint in Drosophila.

Cell

Wu G, Ma T, Hancock CE, Gonzalez S, Aryal B, Vaz S, Chan G, Palarca-Wong M, Allen N, Chung CI, Shu X, Liu Q

Patterning and folding of intestinal villi by active mesenchymal dewetting.

Cell

Huycke TR, Häkkinen TJ, Miyazaki H, Srivastava V, Barruet E, McGinnis CS, Kalantari A, Cornwall-Scoones J, Vaka D, Zhu Q, Jo H, Oria R, Weaver VM, DeGrado WF, Thomson M, Garikipati K, Boffelli D, Klein OD, Gartner ZJ

A retroviral link to vertebrate myelination through retrotransposon-RNA-mediated control of myelin gene expression.

Cell

Ghosh T, Almeida RG, Zhao C, Mannioui A, Martin E, Fleet A, Chen CZ, Assinck P, Ellams S, Gonzalez GA, Graham SC, Rowitch DH, Stott K, Adams I, Zalc B, Goldman N, Lyons DA, Franklin RJM

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