Assistant Professor
Cardiovascular Research Institute
Research Interests
Computational Cardiology and Imaging
Websites
Faculty Type
Core CVRI Faculty
Research Summary:
In the Cardiac Vision Laboratory we focus on developing imaging methodology that can be used to better diagnose life-threatening heart rhythm disorders and heart disease. Combining techniques from bioengineering, computer vision and artificial intelligence with the physics of complex biological systems, we aim to study the heart’s highly dynamic behavior, and bridge the gap between basic cardiovascular science, high-resolution imaging and numerical modeling.
Publications
Differentiable Cardiac Electrophysiology Simulations for Dynamical State and Parameter Estimation.
ArXiv
AI-enabled motion artefact correction to replace emission- and excitation-ratiometry in cardiac optical mapping: a proof-of-concept study.
Cardiovascular research
Combined emission ratiometry and motion tracking for optical mapping of contracting hearts: Validation with monophasic action potentials.
The Journal of physiology
Inflammation significantly alters mucosal transcriptomic signatures in pediatric inflammatory bowel disease.
Crohn's & colitis 360
Panoramic voltage-sensitive optical mapping of contracting hearts using cooperative multiview motion tracking with 12 cameras.
The Journal of physiology
AAV9-mediated KCNH2 suppression-replacement gene therapy in a transgenic rabbit model of type 1 short QT syndrome.
European heart journal
Differential response to acute ischemia between isolated contracting hearts and hearts perfused with excitation-contraction uncouplers.
American journal of physiology. Heart and circulatory physiology
Perceptions of the German General Population Towards Implementing Artificial Intelligence in Medical Care: A Population-Based Survey.
Studies in health technology and informatics
Dreaming of electrical waves: Generative modeling of cardiac excitation waves using diffusion models.
APL machine learning
Paralysis by analysis: Overcoming cardiac contraction with computer vision.
Proceedings of the National Academy of Sciences of the United States of America
Optical mapping of contracting hearts.
The Journal of physiology
Repolarization indicates electrical instability in ventricular arrhythmia originating from papillary muscle.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
Reconstruction of three-dimensional scroll waves in excitable media from two-dimensional observations using deep neural networks.
Physical review. E
Real-Time Optical Mapping of Contracting Cardiac Tissues With GPU-Accelerated Numerical Motion Tracking.
Frontiers in cardiovascular medicine
Rotor Localization and Phase Mapping of Cardiac Excitation Waves Using Deep Neural Networks.
Frontiers in physiology
Direct optogenetic stimulation of smooth muscle cells to control gastric contractility.
Theranostics
Inverse mechano-electrical reconstruction of cardiac excitation wave patterns from mechanical deformation using deep learning.
Chaos (Woodbury, N.Y.)
A comprehensive method protocol for annotation and integrated functional understanding of lncRNAs.
Briefings in bioinformatics
High-Resolution Optical Measurement of Cardiac Restitution, Contraction, and Fibrillation Dynamics in Beating vs. Blebbistatin-Uncoupled Isolated Rabbit Hearts.
Frontiers in physiology
Synchronization-based reconstruction of electromechanical wave dynamics in elastic excitable media.
Chaos (Woodbury, N.Y.)
Marker-Free Tracking for Motion Artifact Compensation and Deformation Measurements in Optical Mapping Videos of Contracting Hearts.
Frontiers in physiology
Electromechanical optical mapping.
Progress in biophysics and molecular biology
Features of Chaotic Transients in Excitable Media Governed by Spiral and Scroll Waves.
Physical review letters
Two Years of tranSMART in a University Hospital for Translational Research and Education.
Studies in health technology and informatics
Optogenetic Light Crafting Tools for the Control of Cardiac Arrhythmias.
Methods in molecular biology (Clifton, N.J.)
Address
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UCSF Box 3120
San Francisco, CA 94158
United States