This NIH T32 funded training program is exclusively postdoctoral. To maximize the impact of this T32 and the number of trainees exposed to its rigorous standards and activities, 8 trainees will be appointed each year for a single year of T32 funding, then rotate off to support provided by individual fellowship grants, grants on which the mentor is PI or other laboratory funds. All trainees will hold PhD, MD, or MD/PhD degrees. Two T32-funded positions will be dedicated to MD or MD/PhD Cardiology fellows (or occasionally other clinical fellows in disciplines relevant to cardiovascular biology and disease) seeking rigorous training in patient-based research through UCSF's TICR program. The remaining trainees will be a mix of PhD, MD, and MD/PhD trainees recruited into CVRI laboratories by individual mentors.
All trainees appointed to the T32 are required to take the Responsible Conduct of Research course. In addition, MD-trained program trainees engaged in clinical research have the option to take formal coursework for training or advanced training in clinical research. Partial tuition for TICR-based trainees will be covered by the program. Opportunities for Laboratory-based Research Track appointees are also available – the trainee will discuss possible coursework opportunities with the Advisor and primary mentor in their initial meeting. Trainees will be encouraged to take the graduate school course(s) relevant to their areas of interest if they have not had similar courses in their prior training.
Although coursework is available, the heart of this training program is formulation and execution of a substantial research project relevant to cardiovascular biology and disease (broadly defined) and development of professional skills under the guidance of a faculty mentor. This core research training is supplemented by co-, group- and peer-mentoring, and by coursework tailored to a trainee’s specific needs. Coursework is particularly intensive for the TICR track, which grounds MD-trained appointees in clinical research. In the laboratory-based research track, trainees have usually selected a primary mentor and apply to the program with support from that investigator. Entering Cardiology fellows who apply to the laboratory-based research track or TICR tracks will be aided in their selection of a primary mentor by Dr. Javid Moslehi. When the primary mentor is a junior faculty member, an advisory committee of co-mentors is provided. Otherwise, the primary mentor and trainee select co-mentors as appropriate for complementary knowledge and skills that support the project. Group and peer mentoring will occur in CVRIPS at which trainees present ongoing work to the entire community, laboratory group meetings, thematic research-in-progress groups, daily interactions in the laboratory, and other venues to facilitate formal and informal scientific interaction.
To apply for a position on the CVRI’s T32, please send by email a cover letter including a brief statement of your research interests and accomplishments with your curriculum vitae directly to the Program Faculty Member/s of interest to you. Applications to the NIH T32 training grant will be made jointly with the faculty member. Program faculty members are listed below.
Christopher Allen(link is external)
Mechanisms of allergic lung inflammation
Kaveh Ashrafi(link is external)
Metabolic regulation of neural functions during aging
Kamran Atabai(link is external)
Limiting fibrosis through cell-mediated collagen turnover
Brian Black(link is external)
Gene Regulatory Networks in cardiovascular development and regeneration
Benoit Bruneau(link is external)
Heart development/congenital heart disease
Abigail Buchwalter(link is external)
Function and dynamic regulation of the nuclear lamina
Daniele Canzio(link is external)
Regulation of clustered Protocadherins;neuronal cell-surface diversity
John Chorba(link is external)
Chemical Biology of Cardiometabolic Disease
Jan Christoph(link is external)
Computational cardiology, cardiac arrhythmia mechanisms and imaging
Pao-Tien Chuang(link is external)
The mechanisms of lung branching and alveolar formation
William Degrado(link is external)
Protein Design, Drug Design, Integrin structure/function, Fibrosis
John Fahy(link is external)
Airway biology and molecular phenotypes of airway diseases
Trevor Fidler(link is external)
Macrophages and atherosclerosis
Jeffrey R. Fineman (link is external)
Pediatric Pulmonary Vascular Disorders
Edward Gerstenfeld(link is external)
Mechanism of ectopy induced remodeling in cardiac arrhythmias
Douglas Gould(link is external)
Biological functions and pathogenic contributions of extracellular matrix
Michael Grabe(link is external)
Computational approaches to structure/function of membrane proteins
Akiko Hata(link is external)
Pathogenesis of vascular disease and deregulation of TGFbeta signaling
Robert A. Hiatt(link is external)
Epidemiology; cancer; social determinants; health disparities
Guo Huang(link is external)
Heart regeneration
Roshanak Irannejad(link is external)
Subcellular GPCR signaling in the cardiovascular system
Isha Jain(link is external)
Oxygen and vitamin metabolism and treatment
Lily Jan(link is external)
Studies of calcium-activated ion channels and lipid scramblases
David Julius(link is external)
Molecular biology of somatosensation and pain
Natalia Jura(link is external)
Regulation of growth factor signaling by ubiquitination
Tom Kornberg(link is external)
Organogenesis and patterning during Drosophila development
Mark Looney(link is external)
Immunobiology of the normal and injured lung
Dengke Ma(link is external)
Molecular genetic basis of physiological resilience in animals
Takashi Mikawa(link is external)
Developmental regulation of organogenesis
Daniel Minor(link is external)
Structure, function, and pharmacology of ion channels
Javid J. Moslehi(link is external)
Cardiovascular complications of novel targeted cancer therapies
Maxence V. Nachury(link is external)
Quality control of the primary cilium proteome
Jose Angel Nicolas-Avila(link is external)
Macrophages and cardiovascular quality control
Elphege P. Nora(link is external)
Chromosome biology and genomics
Jeffrey Olgin(link is external)
Mechanisms of arrhythmias
Akinyemi Oni-Orisan(link is external)
Pharmaco-genomics
Jeremy Reiter(link is external)
Signaling at the primary cilium, the cell's antenna
Dean Sheppard(link is external)
In vivo biology of integrins
Kevan M. Shokat(link is external)
Chemical approaches to deciphering and controlling signal transduction
Xiaokun Shu(link is external)
Protein engineering; Fluorescence reporters; biomolecular condensates
Anthony K. Shum(link is external)
Study of the intersection of autoimmunity with cardiopulmonary disease
Deepak Srivastava(link is external)
Molecular and genetic dissection of cardiogenesis
Christina V. Theodoris(link is external)
Gene Regulatory Networks in Cardiovascular Disease
Geoffrey H. Tison(link is external)
Cardiovascular disease phenotyping and prediction, machine learning
Zian Tseng(link is external)
Heart rhythm
Vasanth Vedantham(link is external)
Heart rhythm
Biao Wang(link is external)
Energy metabolism in adipocytes
Lei Wang(link is external)
Genetically encoding unnatural amino acids and biotherapeutics
Rong Wang(link is external)
Molecular programming of the vasculature in development/disease
Orion Weiner(link is external)
Cell polarity
Balyn W. Zaro(link is external)
Innate immunity in human disease, therapeutic development