
Professor
Medicine
Email
+1 415 353-2873
Faculty Type
Affiliate Faculty
Research Interests: Nuclear medicine, nuclear cardiology, PET/CT, MRI, CT, cardiac cardiology, echocardiology, nuclear magnetic resonance, cardiovascular imaging, stress testimg, heart, myocardial perfusion, scintigraphy, coronary, sychrony, sychronization Summary: My research centers on a collaborative effort to develop noninvasive imaging methods for the identification and evaluation of cardiac anatomy and pathophysiology, and apply them to the diagnosis, risk stratification and monitoring of clinical disease. The work is centered on nuclear medicine methods, PET and SPECT, as well as echocardiography, MRI, and CT.
Publications
Assessment of late-term progression of cardiac allograft vasculopathy in patients with orthotopic heart transplantation using quantitative cardiac 82Rb PET.
The international journal of cardiovascular imaging
The beginnings of ASNC.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
A combined static-dynamic single-dose imaging protocol to compare quantitative dynamic SPECT with static conventional SPECT.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Noninvasive PET quantitative myocardial blood flow with regadenoson for assessing cardiac allograft vasculopathy in orthotopic heart transplantation patients.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Utility of Equilibrium Radionuclide Angiogram-Derived Measures of Dyssynchrony to Predict Outcomes in Heart Failure Patients Undergoing Cardiac Resynchronization Therapy.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Measurement of absolute myocardial blood flow in humans using dynamic cardiac SPECT and 99mTc-tetrofosmin: Method and validation.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Image reconstruction in higher dimensions: myocardial perfusion imaging of tracer dynamics with cardiac motion due to deformation and respiration.
Physics in medicine and biology
Erratum to: Isolated right ventricular cardiac sarcoidosis demonstrated by (18)FDG positron emission tomography.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Quantitative Signature of Coronary Steal in a Patient with Occluded Coronary Arteries Supported by Collateral Circulation Using Dynamic SPECT.
IEEE Nuclear Science Symposium conference record. Nuclear Science Symposium
Isolated right ventricular cardiac sarcoidosis demonstrated by ¹⁸FDG positron emission tomography.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Imaging synchrony.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
The variable functional effects of the pacing site in normal and scarred ventricles.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
The relationship of myocardial contraction and electrical excitation--the correlation between scintigraphic phase image analysis and electrophysiologic mapping.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
A pilot study of changes in (18)F-FDG uptake, calcification and global metabolic activity of the aorta with aging.
Hellenic journal of nuclear medicine
Current methods of pharmacologic stress testing and the potential advantages of new agents.
Journal of nuclear medicine technology
Localization of ventricular tachycardia exit site and subsequent contraction sequence and functional effects with bedside radionuclide angiography.
JACC. Cardiovascular imaging
Age-related decrease in cardiopulmonary adrenergic neuronal function in children as assessed by I-123 metaiodobenzylguanidine imaging.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Myocardial perfusion and function: single photon emission computed tomography.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
The aging of the heart and blood vessels: a consideration of anatomy and physiology in the era of computed tomography, magnetic resonance imaging, and positron emission tomographic imaging methods with special consideration of atherogenesis.
Seminars in nuclear medicine
Equilibrium radionuclide angiocardiography.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
A novel approach to multipinhole SPECT for myocardial perfusion imaging.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
A unique method by which to quantitate synchrony with equilibrium radionuclide angiography.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Clinical value of attenuation correction in stress-only Tc-99m sestamibi SPECT imaging.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Increased right ventricular activity: artifact of camera head misalignment.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Scintigraphic blood pool and phase image analysis: the optimal tool for the evaluation of resynchronization therapy.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Unique contraction pattern in patients after coronary bypass graft surgery by gated SPECT myocardial perfusion imaging.
Clinical nuclear medicine
Current practice. The role of noninvasive testing and affect of VANQWISH/FRISC II trials on managing acute coronary syndrome patients.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Intrinsic dual-energy processing of myocardial perfusion images.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Long-term estrogen replacement therapy is associated with improved exercise capacity in postmenopausal women without known coronary artery disease.
American heart journal
Ventricular contraction abnormalities in dilated cardiomyopathy: effect of biventricular pacing to correct interventricular dyssynchrony.
Journal of the American College of Cardiology
An unusual presentation of non-Hodgkin's lymphoma: a case report.
Clinical nuclear medicine
Impact of a home-based walking and resistance training program on quality of life in patients with heart failure.
The American journal of cardiology
Effects of the repeated administration of adenosine and heparin on myocardial perfusion in patients with chronic stable angina pectoris.
The American journal of cardiology
Is there any advantage to the acquisition of 24-hour thallium images, in the presence of persistent perfusion defects at 4 h after reinjection?
European journal of nuclear medicine
Potential added value of three-dimensional reconstruction and display of single photon emission computed tomographic gated blood pool images.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Nonperfusion applications in nuclear cardiology: report of a task force of the American Society of Nuclear Cardiology.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Fast acquisition of myocardial SPECT images with Tc-99m sestamibi for the diagnosis of coronary artery disease.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Comparison of adenosine to dipyridamole in degree of coronary hyperemic response in heart transplant recipients.
The American journal of cardiology
Diagnostic utility of tomographic myocardial perfusion imaging with technetium 99m furifosmin (Q12) compared with thallium 201: results of a phase III multicenter trial.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Cardiac activation mapping by MRI.
Magma (New York, N.Y.)
Stress imaging. Current clinical options for the diagnosis, localization, and evaluation of coronary artery disease.
The Medical clinics of North America
Acute and chronic effects of transient myocardial ischemia on sympathetic nerve activity, density, and norepinephrine content.
Cardiovascular research
Variability of normal coronary anatomy: implications for the interpretation of thallium-SPECT myocardial perfusion images in single-vessel disease.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Segmental analysis of resting echocardiographic function and stress scintigraphic perfusion: implications for myocardial viability.
American heart journal
A consideration of current clinical options for stress imaging in the diagnosis and evaluation of coronary artery disease.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Effects of long-term right ventricular apical pacing on left ventricular perfusion, innervation, function and histology.
Journal of the American College of Cardiology
Does myocardial perfusion scintigraphy demonstrate clinical usefulness in patients with markedly positive exercise tests? An assessment of the method in a high-risk subset.
American heart journal
Assessment of perfused left ventricular mass in normal, ischemic, and reperfused myocardium by means of single-photon emission computed tomography of technetium-99m isonitrile.
American heart journal
Effects of canine myocardial infarction on sympathetic efferent neuronal function: scintigraphic and electrophysiologic correlates.
American heart journal
Hypertrophic cardiomyopathy in the young: another form of ischemic cardiomyopathy?
Journal of the American College of Cardiology
Myocardial perfusion scintigraphy in left bundle branch block: a perspective on the issue from image analysis in a clinical context.
American heart journal
Myocardial viability: evidence provided by the analysis of left ventricular systolic function.
Coronary artery disease
The proper tool for the job.
Journal of the American College of Cardiology
Basal interventricular septal thallium-201 defects: real or artifact?
Clinical nuclear medicine
A quantitative assessment of patient motion and its effect on myocardial perfusion SPECT images.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Diagnostic and prognostic value of ambulatory electrocardiographic monitoring.
American heart journal
Scintigraphic assessment of MIBG uptake in globally denervated human and canine hearts--implications for clinical studies.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Usefulness of adenosine in augmenting ventricular preexcitation for noninvasive localization of accessory pathways.
The American journal of cardiology
Advances in myocardial scintigraphy in coronary heart disease.
American journal of cardiac imaging
Comparison of the findings on preoperative dipyridamole perfusion scintigraphy and intraoperative transesophageal echocardiography: implications regarding the identification of myocardium at ischemic risk.
Journal of the American College of Cardiology
Dipyridamole perfusion scintigraphy.
Seminars in nuclear medicine
Phase image triangulation of accessory pathways in patients undergoing catheter ablation of posteroseptal pathways.
Pacing and clinical electrophysiology : PACE
Scintigraphic assessment of sympathetic innervation after transmural versus nontransmural myocardial infarction.
Journal of the American College of Cardiology
Relative importance of activation sequence compared to atrioventricular synchrony in left ventricular function.
The American journal of cardiology
Dipyridamole perfusion scintigraphy: the experience with its application in one hundred seventy patients with known or suspected unstable angina.
American heart journal
Benefits of physiologic atrioventricular synchronization for pacing with an exercise rate response.
The American journal of cardiology
Imaging of the heart using metaiodobenzylguanidine.
Journal of thoracic imaging
"Hot spot" imaging agents for acute myocardial infarction.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Epicardial and endocardial localized 31P magnetic resonance spectroscopy: evidence for metabolic heterogeneity during regional ischemia.
Magnetic resonance in medicine
Late reversibility: a viability issue.
Journal of the American College of Cardiology
Oblique reformatting of multislice magnetic resonance images for improved visualization of coronary arteries.
Journal of digital imaging
Blood pool scintigraphy.
Cardiology clinics
Noninvasive assessment of cardiomyopathy in normotensive diabetic patients between 20 and 50 years old.
The American journal of medicine
Response of myocardial metabolites to graded regional ischemia: 31P NMR spectroscopy of porcine myocardium in vivo.
Circulation research
Value of color Doppler estimation of regurgitant volume in patients with chronic aortic insufficiency.
American heart journal
ECG left anterior fascicular block reveals diverse patterns on scintigraphic phase analysis.
American heart journal
The scintigraphic characteristics of ventricular pre-excitation through Mahaim fibers with the use of phase analysis.
Journal of the American College of Cardiology
Nuclear magnetic resonance imaging-guided phosphorus-31 spectroscopy of the human heart.
Journal of the American College of Cardiology
The clinical and pathophysiologic implications of pain, ST abnormalities, and scintigraphic changes induced during dipyridamole infusion: their relationships to the peripheral hemodynamic response.
American heart journal
In vivo alterations of high-energy phosphates and intracellular pH during reversible ischemia in pigs: a 31P magnetic resonance spectroscopy study.
American heart journal
Dipyridamole myocardial perfusion scintigraphy.
The Western journal of medicine
Estimation of the functional and anatomic extent of myocardial infarction using magnetic resonance imaging.
American heart journal
Analysis of thallium-201 "washout" from parametric color coded images.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Substrate regulation of the nucleotide pool during regional ischaemia and reperfusion in an isolated rat heart preparation: a phosphorus-31 magnetic resonance spectroscopy analysis.
Cardiovascular research
Chemomechanics of altered perfusion pressure in rat hearts.
Basic research in cardiology
Quantitation of intracardiac shunts by cine-CT.
Journal of computer assisted tomography
Segmental evaluation of left ventricular wall motion after myocardial infarction: magnetic resonance imaging versus echocardiography.
American heart journal
Factors influencing myocardial response to metabolic acidosis in isolated rat hearts.
The American journal of physiology
Augmented preexcitation assessed by scintigraphic phase analysis during atrial pacing.
American heart journal
Effects of altered coronary perfusion pressure on function and metabolism of normal and cardiomyopathic hamster hearts.
Journal of molecular and cellular cardiology
Hemodynamic and clinical evaluation of piroximone, a new inotrope-vasodilator agent, in severe congestive heart failure.
Journal of the American College of Cardiology
Advances in noninvasive cardiovascular imaging: implications for the anesthesiologist.
Anesthesiology
Left ventricular dimensions and mechanics in distance runners.
American heart journal
Quantitation of regional myocardial function by cine computed tomography: pharmacologic changes in wall thickness.
Journal of the American College of Cardiology
Cine-computed tomography of Ebstein anomaly.
Journal of computer assisted tomography
Noninvasive quantitation of the left heart by echocardiography and scintigraphy.
Cardiovascular clinics
Effects of intravenous administration of a new nonionic dimeric contrast medium on the coronary circulation. Comparison with monomeric ionic and nonionic media.
Investigative radiology
Measurement of cardiac output by cine computed tomography.
The American journal of cardiology
Interaction of "supplementary" scintigraphic indicators of ischemia and stress electrocardiography in the diagnosis of multivessel coronary disease.
Journal of the American College of Cardiology
Undrained bloody pericardial effusion in the early postoperative period after coronary bypass surgery: a prospective blood pool study.
American heart journal
[Imaging of the heart using nuclear magnetic resonance tomography. I: Tomography].
Zeitschrift fur Kardiologie
The etiology and implications of dense cavitary "photopenia" on myocardial perfusion scintigraphy.
Investigative radiology
Normal cardiac dimensions by magnetic resonance imaging.
The American journal of cardiology
Magnetic resonance imaging in hypertrophic cardiomyopathy.
The American journal of cardiology
Detection and characterization of acute myocardial infarction in man with use of gated magnetic resonance.
Circulation
[Diagnosis of left bundle branch block with the phase analysis of radionuclide images].
Zhonghua xin xue guan bing za zhi
Assessment of left intraventricular block by scintigraphic analysis.
Chinese medical journal
Assessment of cardiac anatomy using nuclear magnetic resonance imaging.
Journal of the American College of Cardiology
Cardiosynchronous MRI intensity changes of the great vessels and pulmonary circulation. A preliminary report.
Annales de radiologie
Magnetic resonance (MR) imaging of aorta and pulmonary circulation. Initial experience with ECG-gating.
Annales de radiologie
Mechanisms of improved left ventricular function following intravenous MDL 17,043 in patients with severe chronic heart failure.
American heart journal
Phase image characterization of localized and generalized left ventricular contraction abnormalities.
Journal of the American College of Cardiology
The scintigraphic identification of "severe myocardial ischemia".
Giornale italiano di cardiologia
Value of noninvasive assessment of patients with atypical chest pain and suspected coronary spasm using ergonovine infusion and thallium-201 scintigraphy.
The American journal of cardiology
Catheter-induced His bundle ablation in a patient with reentrant tachycardia associated with a nodoventricular tract.
Journal of the American College of Cardiology
Right ventricular myocardial infarction with ventricular septal rupture.
American heart journal
Improved regional ventricular function after successful surgical revascularization.
Journal of the American College of Cardiology
Phase image evaluation of patients with ventricular pre-excitation syndromes.
Journal of the American College of Cardiology
Characterization of conduction and concentration abnormalities by scintigraphic phase analysis.
International journal of cardiology
Imaging and characterization of acute myocardial infarction in vivo by gated nuclear magnetic resonance.
Circulation
The functional implications of scintigraphic measures of myocardial ischemia and infarction.
American heart journal
Diagnostic test use in different practice settings. A controlled comparison.
Archives of internal medicine
Evaluation of the post-coronary artery bypass patient by myocardial perfusion scintigraphy and computed tomography.
AJR. American journal of roentgenology
Cardiovascular imaging with nuclear magnetic resonance.
Cardiology clinics
Volume loading improves low cardiac output in experimental right ventricular infarction.
Journal of the American College of Cardiology
Nuclear magnetic resonance imaging of the cardiovascular system: normal and pathologic findings.
Radiology
Late prognostic value of scintigraphic parameters of acute myocardial infarction size in complicated myocardial infarction without heart failure.
The American journal of cardiology
Variability in coronary hemodynamics in response to ergonovine in patients with normal coronary arteries and atypical chest pain.
Journal of the American College of Cardiology
Electrophysiologic mechanism of exercise-induced sustained ventricular tachycardia.
The American journal of cardiology
What is the reliability and the utility of scintigraphic methods for the assessment of ventricular function?
Cardiovascular clinics
The late prognostic value of acute scintigraphic measurement of myocardial infarction size.
Circulation
An accurate means of detecting and characterizing abnormal patterns of ventricular activation by phase image analysis.
The American journal of cardiology
Phase image characterization of ventricular contraction in left and right bundle branch block.
The American journal of cardiology
Diagnostic accuracy of cardiologists compared with probability calculations using Bayes' rule.
The American journal of cardiology
Hemodynamic benefit of atrial pacing in right ventricular myocardial infarction.
Annals of internal medicine
The significance of nitroglycerin-induced changes in ventricular function after acute myocardial infarction.
The American journal of cardiology
Are regions of ischaemia detected on stress perfusion scintigraphy predictive of sites of subsequent myocardial infarction?
British heart journal
Detecting and localizing peripheral arterial disease: assessment of 201Tl scintigraphy.
AJR. American journal of roentgenology
The inconsistent pattern of thallium defects: a clue to the false positive perfusion scintigram.
The American journal of cardiology
Contrast enhancement of thallium-201 myocardial scintigrams: improved sensitivity with diminished specificity in coronary disease detection.
American heart journal
Evaluation of left ventricular performance by gated radionuclide angiography.
Clinical nuclear medicine
A consideration of factors affecting the diagnostic accuracy of thallium-201 myocarial perfusion scintigraphy in detecting coronary artery disease.
Seminars in nuclear medicine
Myocardial perfusion scintigraphy.
Archives of internal medicine
Correlation of thallium-201 scintigrams with coronary anatomy: factors affecting region by region sensitivity.
The American journal of cardiology
Myocardial scintigraphy with technetium-99m stannous pyrophosphate: an insensitive test for nontransmural myocardial infarction.
The American journal of cardiology
The specificity of pyrophosphate myocardial scintigrams in patients with prior myocardial infarction: concise communication.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Thallium-201 myocardial perfusion scintigraphy to evaluate patients after coronary bypass surgery.
The American journal of cardiology
The clinical estimation of acute myocardial infarct size with 99mTechnetium pyrophosphate scintigraphy.
Circulation
Myocardial scintigraphy in coronary artery disease.
Cleveland Clinic quarterly
Thallium-20 1 myocardial perfusion scintigraphy for the clinical clarification of normal, abnormal and equivocal electrocardiographic stress tests.
The American journal of cardiology
Acute myocardial infarction: clinical application of technetium 99m stannous pyrophosphate infarct scintigraphy.
The Western journal of medicine
Myocardial stress perfusion scintigraphy with rubidium-81 versus stress electrocardiography.
The American journal of cardiology
The hemodynamics of coronary arterial stenosis.
Cardiovascular clinics
Noninvasive diagnosis of a false left ventricular aneurysm with radioisotope gated cardiac blood pool imaging. Differentiation from true aneurysm.
The American journal of cardiology
Myocardial infarction in closed-chest dogs: a simplified method for production.
Journal of applied physiology
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