Michael Grabe, PhD
Professor
Cardiovascular Research Institute
Address:
555 Mission Bay Blvd South, Rm 452T
UCSF Box 3122
San Francisco, CA 94158
United StatesPhone:
+1 415 502-2874
Email:
Research Summary:
Our lab uses computational methods to understand biological phenomena. We are primarily interested in the mechanical operation of ion channels and transporters, which move ions and small molecules across membranes. Additionally, we use theoretical approaches to explore how these membrane proteins work together to regulate ion homeostasis in organelles such as the lysosome and Golgi. Lastly, we are developing methodologies for predicting the stability of membrane proteins to understand how mutations give rise to a loss of function, improper trafficking or degradation.
Education and Training:
07/2021
University of California, San Francisco
Diversity, Equity, and Inclusion Champion Training
Diversity, Equity, and Inclusion Champion Training
07/2021
University of California, San Francisco
Diversity, Equity, and Inclusion Champion Training
Diversity, Equity, and Inclusion Champion Training
Research Activities And Funding:
Jan 1, 2021 - Nov 30, 2024
Ion permeation, lipid flipping, and membrane remodeling by TMEM16 proteins
NIH R01GM137109
Role: Principal Investigator
NIH R01GM137109
Role: Principal Investigator
Sep 1, 2012 - Jul 31, 2015
Computer simulations of lysosomal and osteoclast microphysiology
NIH R21GM100224
Role: Principal Investigator
NIH R21GM100224
Role: Principal Investigator
Publications:
Websites:
ORCID:
0000-0003-3509-5997 Additional info
Faculty Type:
Core CVRI Faculty