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The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis.

Blood

Senis YA, Tomlinson MG, Ellison S, Mazharian A, Lim J, Zhao Y, Kornerup KN, Auger JM, Thomas SG, Dhanjal T, Kalia N, Zhu JW, Weiss A, Watson SP

SHIP prevents lipopolysaccharide from triggering an antiviral response in mice.

Blood

Sly LM, Hamilton MJ, Kuroda E, Ho VW, Antignano FL, Omeis SL, van Netten-Thomas CJ, Wong D, Brugger HK, Williams O, Feldman ME, Houseman BT, Fiedler D, Shokat KM, Krystal G

Increased Thrombosis in Vivo and Altered Coagulation in Vitro in STAT5AB-Deficient Mice.

Blood

Sarah M Nordstrom, Brandon C Sos, Katelyn M Dow, Tina S Fong, Robert E Levy, Jonathan Dukes, Ethan J Weiss

A Novel Tissue Factor Resistance Locus on Mouse Chromosome 11 Confers Protection from Thrombosis through Reduced Activity of Factor XI.

Blood

Katelyn M Dow, Sarah M Nordstrom, Brandon C Sos, Richard C Davis, Aldons J Lusis, Ethan J Weiss

Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure.

Blood

Minamishima YA, Moslehi J, Bardeesy N, Cullen D, Bronson RT, Kaelin WG

Gene therapy improves immune function in preadolescents with X-linked severe combined immunodeficiency.

Blood

Chinen J, Davis J, De Ravin SS, Hay BN, Hsu AP, Linton GF, Naumann N, Nomicos EY, Silvin C, Ulrick J, Whiting-Theobald NL, Malech HL, Puck JM

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