Genome biology

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AlleleAnalyzer: a tool for personalized and allele-specific sgRNA design.

Genome biology

Keough KC, Lyalina S, Olvera MP, Whalen S, Conklin BR, Pollard KS

ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues.

Genome biology

Mangul S, Yang HT, Strauli N, Gruhl F, Porath HT, Hsieh K, Chen L, Daley T, Christenson S, Wesolowska-Andersen A, Spreafico R, Rios C, Eng C, Smith AD, Hernandez RD, Ophoff RA, Santana JR, Levanon EY, Woodruff PG, Burchard E, Seibold MA, Shifman S, Eskin E, Zaitlen N

OMSV enables accurate and comprehensive identification of large structural variations from nanochannel-based single-molecule optical maps.

Genome biology

Li L, Leung AK, Kwok TP, Lai YYY, Pang IK, Chung GT, Mak ACY, Poon A, Chu C, Li M, Wu JJK, Lam ET, Cao H, Lin C, Sibert J, Yiu SM, Xiao M, Lo KW, Kwok PY, Chan TF, Yip KY

Prioritizing causal disease genes using unbiased genomic features.

Genome biology

Deo RC, Musso G, Tasan M, Tang P, Poon A, Yuan C, Felix JF, Vasan RS, Beroukhim R, De Marco T, Kwok PY, MacRae CA, Roth FP

Prediction of LDL cholesterol response to statin using transcriptomic and genetic variation.

Genome biology

Kim K, Bolotin E, Theusch E, Huang H, Medina MW, Krauss RM

The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage.

Genome biology

Shaffer HB, Minx P, Warren DE, Shedlock AM, Thomson RC, Valenzuela N, Abramyan J, Amemiya CT, Badenhorst D, Biggar KK, Borchert GM, Botka CW, Bowden RM, Braun EL, Bronikowski AM, Bruneau BG, Buck LT, Capel B, Castoe TA, Czerwinski M, Delehaunty KD, Edwards SV, Fronick CC, Fujita MK, Fulton L, Graves TA, Green RE, Haerty W, Hariharan R, Hernandez O, Hillier LW, Holloway AK, Janes D, Janzen FJ, Kandoth C, Kong L, de Koning AP, Li Y, Literman R, McGaugh SE, Mork L, O'Laughlin M, Paitz RT, Pollock DD, Ponting CP, Radhakrishnan S, Raney BJ, Richman JM, St John J, Schwartz T, Sethuraman A, Spinks PQ, Storey KB, Thane N, Vinar T, Zimmerman LM, Warren WC, Mardis ER, Wilson RK

A high resolution map of a cyanobacterial transcriptome.

Genome biology

Vijayan V, Jain IH, O'Shea EK

Membrane traffic in the post-genomic era.

Genome biology

Peter Hein, Mark von Zastrow

Towards accurate imputation of quantitative genetic interactions.

Genome biology

Ulitsky I, Krogan NJ, Shamir R

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