Immunity

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Regulation of CD1 function and NK1.1(+) T cell selection and maturation by cathepsin S.

Immunity

Riese RJ, Shi GP, Villadangos J, Stetson D, Driessen C, Lennon-Dumenil AM, Chu CL, Naumov Y, Behar SM, Ploegh H, Locksley R, Chapman HA

HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1.

Immunity

Liou J, Kiefer F, Dang A, Hashimoto A, Cobb MH, Kurosaki T, Weiss A

Cathepsin S required for normal MHC class II peptide loading and germinal center development.

Immunity

Shi GP, Villadangos JA, Dranoff G, Small C, Gu L, Haley KJ, Riese R, Ploegh HL, Chapman HA

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway.

Immunity

Finco TS, Kadlecek T, Zhang W, Samelson LE, Weiss A

alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases.

Immunity

van Oers NS, Lowin-Kropf B, Finlay D, Connolly K, Weiss A

Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading.

Immunity

Riese RJ, Wolf PR, Brömme D, Natkin LR, Villadangos JA, Ploegh HL, Chapman HA

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