The Journal of Immunology

Development of uveitis in a mouse model of spontaneous autoimmunity correlates with frequency of autoantigen-specific regulatory T cells.

Mianmian Yin, Kamir J Hiam, Irina Proekt, Jackie Chan, Yongmei Hu, Clifford A Lowell, Douglas B Gould, Matthew Spitzer, Mark S Anderson, Anthony L DeFranco

Autoantigen specific T-cell receptor induces organ-specific autoimmunity by escaping T cell negative selection.

The Journal of Immunology

Mianmian Yin, Jennifer A Smith, Marissa Chou, Jackie Chan, Yongmei Hu, Clifford A Lowell, Douglas B Gould, Mark S Anderson, Anthony L DeFranco

The phosphatidylinositol-transfer protein Nir3 modulates T cell development and function.

The Journal of Immunology

Wen Lu, Ynes A Helou, Byron B Au-Yeung, Krishna Shrinivas, Jen Liou, Arthur Weiss

Overcoming inhibitory constraints to TCR signaling by targeting the pH-sensitive phosphatase suppressor of T-cell receptor signaling 1 (STS1).

The Journal of Immunology

Yuan-Li Tsai, Marcel Arias Badia, Theresa A Kadlecek, Neel H Shah, Lawrence Fong, Arthur Weiss

Interstitial lung disease patients exhibit augmented germinal center responses in lung lymph nodes and increased serum reactivities to novel autoantigens.

The Journal of Immunology

Young me Yoon, Tania Velez, Vaibhav Upadhyay, Sara Vazquez, Cathryn T Lee, Kelly Blaine, Donna Decker, Robert Guzy, Ayodeji Adegunsoye, Mary Strek, Imre Noth, Mark S Anderson, Joseph DeRisi, Anthony Shum, Anne I Sperling