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Depletion of fat-resident Treg cells prevents age-associated insulin resistance.

Nature

Bapat SP, Myoung Suh J, Fang S, Liu S, Zhang Y, Cheng A, Zhou C, Liang Y, LeBlanc M, Liddle C, Atkins AR, Yu RT, Downes M, Evans RM, Zheng Y

Oxygen regulation of breathing through an olfactory receptor activated by lactate.

Nature

Chang AJ, Ortega FE, Riegler J, Madison DV, Krasnow MA

Hedgehog actively maintains adult lung quiescence and regulates repair and regeneration.

Nature

Peng T, Frank DB, Kadzik RS, Morley MP, Rathi KS, Wang T, Zhou S, Cheng L, Lu MM, Morrisey EE

Mutations in DCHS1 cause mitral valve prolapse.

Nature

Durst R, Sauls K, Peal DS, deVlaming A, Toomer K, Leyne M, Salani M, Talkowski ME, Brand H, Perrocheau M, Simpson C, Jett C, Stone MR, Charles F, Chiang C, Lynch SN, Bouatia-Naji N, Delling FN, Freed LA, Tribouilloy C, Le Tourneau T, LeMarec H, Fernandez-Friera L, Solis J, Trujillano D, Ossowski S, Estivill X, Dina C, Bruneval P, Chester A, Schott JJ, Irvine KD, Mao Y, Wessels A, Motiwala T, Puceat M, Tsukasaki Y, Menick DR, Kasiganesan H, Nie X, Broome AM, Williams K, Johnson A, Markwald RR, Jeunemaitre X, Hagege A, Levine RA, Milan DJ, Norris RA, Slaugenhaupt SA

Structure of the TRPA1 ion channel suggests regulatory mechanisms.

Nature

Paulsen CE, Armache JP, Gao Y, Cheng Y, Julius D

Structure of the TRPA1 ion channel suggests regulatory mechanisms.

Nature

Paulsen CE, Armache JP, Gao Y, Cheng Y, Julius D

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.

Nature

Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, Loh ML, Jung JU, Coligan JE, Bolland S, Mak TW, Limnander A, Jumaa H, Reth M, Weiss A, Lowell CA, Müschen M

Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury.

Nature

Vaughan AE, Brumwell AN, Xi Y, Gotts JE, Brownfield DG, Treutlein B, Tan K, Tan V, Liu FC, Looney MR, Matthay MA, Rock JR, Chapman HA

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