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A statin-dependent QTL for GATM expression is associated with statin-induced myopathy.

Nature

Mangravite LM, Engelhardt BE, Medina MW, Smith JD, Brown CD, Chasman DI, Mecham BH, Howie B, Shim H, Naidoo D, Feng Q, Rieder MJ, Chen YD, Rotter JI, Ridker PM, Hopewell JC, Parish S, Armitage J, Collins R, Wilke RA, Nickerson DA, Stephens M, Krauss RM

Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor.

Nature

Peng T, Tian Y, Boogerd CJ, Lu MM, Kadzik RS, Stewart KM, Evans SM, Morrisey EE

Conformational biosensors reveal GPCR signalling from endosomes.

Nature

Irannejad R, Tomshine JC, Tomshine JR, Chevalier M, Mahoney JP, Steyaert J, Rasmussen SG, Sunahara RK, El-Samad H, Huang B, von Zastrow M

High-resolution crystal structure of human protease-activated receptor 1.

Nature

Zhang C, Srinivasan Y, Arlow DH, Fung JJ, Palmer D, Zheng Y, Green HF, Pandey A, Dror RO, Shaw DE, Weis WI, Coughlin SR, Kobilka BK

Drosophila NOMPC is a mechanotransduction channel subunit for gentle-touch sensation.

Nature

Yan Z, Zhang W, He Y, Gorczyca D, Xiang Y, Cheng LE, Meltzer S, Jan LY, Jan YN

Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells.

Nature

Wei P, Wong WW, Park JS, Corcoran EE, Peisajovich SG, Onuffer JJ, Weiss A, Lim WA

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes.

Nature

Qian L, Huang Y, Spencer CI, Foley A, Vedantham V, Liu L, Conway SJ, Fu JD, Srivastava D

Heart repair by reprogramming non-myocytes with cardiac transcription factors.

Nature

Song K, Nam YJ, Luo X, Qi X, Tan W, Huang GN, Acharya A, Smith CL, Tallquist MD, Neilson EG, Hill JA, Bassel-Duby R, Olson EN

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