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Poison Frogs, Birds, Hold Clues to Antidotes for Deadly Toxins

August 05, 2021
A team of researchers at UC San Francisco, the California Academy of Sciences and Stanford University have uncovered some intriguing clues in the mystery of how some poison birds and frogs evade their own toxins. The answer may lead to a much-sought-after antidote to paralytic shellfish poisoning (...
Coronavirus disease 2019 (COVID-19)

Binding of SARS-CoV-2 spike protein to ACE2 is disabled by thiol-based drugs; evidence from in vitro SARS-CoV-2 infection studies

December 08, 2020
Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the SARS-CoV-2 spike protein is an envelope glycoprotein that binds angiotensin converting enzyme 2 as an entry receptor. 

Pulmonary Division, Department of Medicine, Lung Biology Center, and Cardiovascular Research Institute Faculty Search

October 28, 2020
UCSF School of Medicine and Zuckerberg San Francisco General Hospital Pulmonary Division, Department of Medicine, Lung Biology Center, and Cardiovascular Research Institute
Arctic ground squirrel

Cytoprotection by a naturally occurring variant of ATP5G1 in Arctic ground squirrel neural progenitor cell

October 14, 2020
In major cardiovascular diseases, including stroke and heart attack, loss of blood flow causes loss of oxygen (ischemia), leading to tissue damage and cell deaths. A species of ground squirrels from the Arctic can tolerate such ischemic attack, but the underlying biological basis has been unknown.
Titus Fig

The structure of a calsequestrin filament reveals mechanisms of familial arrhythmia

October 12, 2020
In a clinical collaboration with Melvin Scheinman from the UCSF Comprehensive Genetic Arrythmia Program, CVRI investigators Rahul Deo and Natalia Jura, along with MD/PhD trainee Erron Titus, set out to explain how mutations in the calcium-storage protein, calsequestrin, cause lethal arrhthymias....
finger on smartphone

A digital biomarker of diabetes from smartphone-based vascular signals

August 17, 2020
The global burden of diabetes is rapidly increasing, from 451 million people in 2019 to 693 million by 2045
Dr. Ethan Weiss

These San Francisco doctors flew to New York to fight the coronavirus — and they have a warning for us

July 07, 2020
 When Dr. Ethan Weiss arrived in New York in late April, he started his first shift almost immediately.
UCSF’s Dr. Michael Matthay

UCSF studying stem cells as possible coronavirus treatment

June 11, 2020
UCSF’s Dr. Michael Matthay wasn’t thinking about a pandemic in January when he launched a clinical trial to investigate whether certain stem cells could effectively treat a serious form of respiratory failure.

2020 Chen Award for Distinguished Academic Achievement in Human Genetic and Genomic Research

April 05, 2020
Pui-Yan Kwok, MD, PhD This award is to celebrate the achievement of a biomedical scientist:

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