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Functional overlap and regulatory links shape genetic interactions between signaling pathways.

Cell

van Wageningen S, Kemmeren P, Lijnzaad P, Margaritis T, Benschop JJ, de Castro IJ, van Leenen D, Groot Koerkamp MJ, Ko CW, Miles AJ, Brabers N, Brok MO, Lenstra TL, Fiedler D, Fokkens L, Aldecoa R, Apweiler E, Taliadouros V, Sameith K, van de Pasch LA, van Hooff SR, Bakker LV, Krogan NJ, Snel B, Holstege FC

Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains.

Cell

Puthenveedu MA, Lauffer B, Temkin P, Vistein R, Carlton P, Thorn K, Taunton J, Weiner OD, Parton RG, von Zastrow M

Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors.

Cell

Ieda M, Fu JD, Delgado-Olguin P, Vedantham V, Hayashi Y, Bruneau BG, Srivastava D

The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia.

Cell

Jin H, White SR, Shida T, Schulz S, Aguiar M, Gygi SP, Bazan JF, Nachury MV

Compete globally, bud locally.

Cell

Houk AR, Millius A, Weiner OD

Polarity is destiny.

Cell

Cai L, Mostov K

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