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TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents.

Cell

Bautista DM, Jordt SE, Nikai T, Tsuruda PR, Read AJ, Poblete J, Yamoah EN, Basbaum AI, Julius D

A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator.

Cell

Downey M, Houlsworth R, Maringele L, Rollie A, Brehme M, Galicia S, Guillard S, Partington M, Zubko MK, Krogan NJ, Emili A, Greenblatt JF, Harrington L, Lydall D, Durocher D

Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.

Cell

Keogh MC, Kurdistani SK, Morris SA, Ahn SH, Podolny V, Collins SR, Schuldiner M, Chin K, Punna T, Thompson NJ, Boone C, Emili A, Weissman JS, Hughes TR, Strahl BD, Grunstein M, Greenblatt JF, Buratowski S, Krogan NJ

Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile.

Cell

Schuldiner M, Collins SR, Thompson NJ, Denic V, Bhamidipati A, Punna T, Ihmels J, Andrews B, Boone C, Greenblatt JF, Weissman JS, Krogan NJ

The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient.

Cell

Costantini DL, Arruda EP, Agarwal P, Kim KH, Zhu Y, Zhu W, Lebel M, Cheng CW, Park CY, Pierce SA, Guerchicoff A, Pollevick GD, Chan TY, Kabir MG, Cheng SH, Husain M, Antzelevitch C, Srivastava D, Gross GJ, Hui CC, Backx PH, Bruneau BG

Common molecular pathways mediate long-term potentiation of synaptic excitation and slow synaptic inhibition.

Cell

Huang CS, Shi SH, Ule J, Ruggiu M, Barker LA, Darnell RB, Jan YN, Jan LY

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